Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Nov;2(11):e658-e659.
doi: 10.1016/S2665-9913(20)30345-3. Epub 2020 Sep 25.

Genetic variants mimicking therapeutic inhibition of IL-6 receptor signaling and risk of COVID-19

Affiliations

Genetic variants mimicking therapeutic inhibition of IL-6 receptor signaling and risk of COVID-19

Jonas Bovijn et al. Lancet Rheumatol. 2020 Nov.
No abstract available

PubMed Disclaimer

References

    1. Biran N, Ip A, Ahn J. Tocilizumab among patients with COVID-19 in the intensive care unit: a multicentre observational study. Lancet Rheumatol. 2020 doi: 10.1016/S2665-9913(20)30277-0. published online Aug 14. - DOI - PMC - PubMed
    1. Georgakis MK, Malik R, Gill D. Interleukin-6 signaling effects on ischemic stroke and other cardiovascular outcomes: a mendelian randomization study. Circ Genom Precis Med. 2020;13 - PMC - PubMed
    1. COVID-19 Host Genetics Initiative The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. Eur J Hum Genet. 2020;28:715–718. - PMC - PubMed
    1. Interleukin-6 Receptor Mendelian Randomisation Analysis (IL6R MR) Consortium. Swerdlow DI, Holmes MV. The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet. 2012;379:1214–1224. - PMC - PubMed
    1. Regeneron Regeneron and Sanofi provide update on Kevzara (sarilumab) phase 3 U.S. trial in COVID-19 patients. July 2, 2020. https://investor.regeneron.com/news-releases/news-release-details/regene...

LinkOut - more resources