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Review
. 2021 Jan 11;34(1):doaa105.
doi: 10.1093/dote/doaa105.

How to approach adult patients with asymptomatic esophageal eosinophilia

Philipp Schreiner  1 , Luc Biedermann  1 , Thomas Greuter  1 , Benjamin L Wright  2   3 , Alex Straumann  1
Affiliations
Review

How to approach adult patients with asymptomatic esophageal eosinophilia

Philipp Schreiner et al. Dis Esophagus. .

Abstract

As the awareness among gastroenterologists regarding endoscopic features suggesting eosinophilic esophagitis is increasing, individuals without symptoms of esophageal dysfunction are increasingly being found to have esophageal eosinophilia on biopsies performed during upper gastrointestinal endoscopies. However, the course of disease and the management of these asymptomatic individuals with esophageal eosinophilia remain elusive. In this review, we propose a definition of asymptomatic individuals with esophageal eosinophilia and discuss the prevalence, risk factors, and course of disease of this specific patient group. Furthermore, we have established a diagnostic and therapeutic pathway based on the most recent available data.

Keywords: eosinophilic esophagitis; eosinophilic gastrointestinal disorders; eosinophils.

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Figures

Fig. 1
Fig. 1
Management algorithm for asymptomatic esophageal eosinophilia.
See this image and copyright information in PMC

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