Distinguishing HF with reduced and preserved ejection fraction at the level of individual cardiomyocytes: implications for therapeutic development
- PMID: 33017063
- DOI: 10.1113/JP280739
Distinguishing HF with reduced and preserved ejection fraction at the level of individual cardiomyocytes: implications for therapeutic development
Keywords: excitation-contraction coupling; heart failure.
Comment on
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Distinct features of calcium handling and β-adrenergic sensitivity in heart failure with preserved versus reduced ejection fraction.J Physiol. 2020 Nov;598(22):5091-5108. doi: 10.1113/JP280425. Epub 2020 Sep 9. J Physiol. 2020. PMID: 32829489 Free PMC article.
References
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- Borlaug BA & Redfield MM (2011). Diastolic and systolic heart failure are distinct phenotypes within the heart failure spectrum. Circulation 123, 2006-2014.
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- Eisner DA, Caldwell JL, Trafford AW & Hutchings DC (2020). The control of diastolic calcium in the heart: basic mechanisms and functional implications. Circ Res 126, 395-412.
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- Kilfoil PJ, Lotteau S, Zhang R, Yue X, Aynaszyan S, Solymani RE, Cingolani E, Marbán E & Goldhaber JI (2020). Distinct features of calcium handling and β-adrenergic sensitivity in heart failure with preserved versus reduced ejection fraction. J Physiol 598, 5091-5108.
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- Noll NA, Lal H & Merryman WD (2020). Mouse models of heart failure with preserved or reduced ejection fraction. Am J Pathol 190, 1596-1608.
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