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Review
. 2020 Dec;63(4):770-787.
doi: 10.1097/GRF.0000000000000572.

Bone Health and Osteoporosis Prevention and Treatment

Marcus Muñoz  1 , Kathleen Robinson  2 , Amal Shibli-Rahhal  2
Affiliations
Review

Bone Health and Osteoporosis Prevention and Treatment

Marcus Muñoz et al. Clin Obstet Gynecol. 2020 Dec.

Abstract

Postmenopausal osteoporosis is a common condition and is associated with increased risk of fracture, including hip and vertebral fractures that in turn can have devastating consequences on morbidity and mortality. In this article, we review the pathogenesis and diagnostic approach to postmenopausal osteoporosis. We review available nonpharmacologic and pharmacologic therapies and we discuss their clinical efficacy and complications, with a detailed discussion of atypical femur fractures and osteonecrosis of the jaw.

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References

    1. NIH Consensus Development Panel on Osteoporosis. Osteoporosis prevention, diagnosis, and therapy. JAMA. 2001;285:785–795.
    1. Wright NC, Looker AC, Saag KG, et al. The recent prevalence of osteoporosis and low bone mass in the United States based on bone mineral density at the femoral neck or lumbar spine. J Bone Miner Res. 2014;29:2520–2526.
    1. Eastell R, Rosen CJ, Black DM, et al. Pharmacological management of osteoporosis in postmenopausal women: an endocrine society clinical practice guideline. J Clin Endocrinol Metab. 2019;104:1595–1622.
    1. Riggs BL, Melton LJ, Robb RA, et al. A population-based assessment of rates of bone loss at multiple skeletal sites: evidence for substantial trabecular bone loss in young adult women and men. J Bone Miner Res. 2008;23:205–214.
    1. Kurihara N, Chenu C, Miller M, et al. Identification of committed mononuclear precursors for osteoclast-like cells formed in long term human marrow cultures. Endocrinology. 1990;126:2733–2741.

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