doi: 10.1128/jb.169.8.3821-3822.1987.
Inhibition of purified Escherichia coli leader peptidase by the leader (signal) peptide of bacteriophage M13 procoat
- PMID: 3301818
- PMCID: PMC212473
- DOI: 10.1128/jb.169.8.3821-3822.1987
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Inhibition of purified Escherichia coli leader peptidase by the leader (signal) peptide of bacteriophage M13 procoat
J Bacteriol.
1987 Aug.
Abstract
The leader peptide of bacteriophage M13 procoat inhibited the cleavage of M13 procoat or pre-maltose-binding protein by purified Escherichia coli leader peptidase. This finding confirms inferences that the leader is the primary site of enzyme recognition and suggests a rationale for the rapid hydrolysis of leader peptides in vivo.
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