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Review
. 2020 Oct 1;25(19):4513.
doi: 10.3390/molecules25194513.

Medicinal Potential of Garcinia Species and Their Compounds

Bruna Larissa Spontoni do Espirito Santo  1 , Lidiani Figueiredo Santana  1 , Wilson Hino Kato Junior  2 , Felipe de Oliveira de Araújo  3 , Danielle Bogo  1 , Karine de Cássia Freitas  1 , Rita de Cássia Avellaneda Guimarães  1 , Priscila Aiko Hiane  1 , Arnildo Pott  4 , Wander Fernando de Oliveira Filiú  5 , Marcel Arakaki Asato  6 , Patrícia de Oliveira Figueiredo  7 , Paulo Roberto Haidamus de Oliveira Bastos  1
Affiliations
Review

Medicinal Potential of Garcinia Species and Their Compounds

Bruna Larissa Spontoni do Espirito Santo et al. Molecules. .

Abstract

Garcinia is a genus of Clusiaceae, distributed throughout tropical Asia, Africa, New Caledonia, Polynesia, and Brazil. Garcinia plants contain a broad range of biologically active metabolites which, in the last few decades, have received considerable attention due to the chemical compositions of their extracts, with compounds which have been shown to have beneficial effects in several diseases. Our work had the objective of reviewing the benefits of five Garcinia species (G. brasiliensis, G. gardneriana, G. pedunculata, G. cambogia, and G. mangstana). These species provide a rich natural source of bioactive compounds with relevant therapeutic properties and anti-inflammatory effects, such as for the treatment of skin disorders, wounds, pain, and infections, having demonstrated antinociceptive, antioxidant, antitumoral, antifungal, anticancer, antihistaminic, antiulcerogenic, antimicrobial, antiviral, vasodilator, hypolipidemic, hepatoprotective, nephroprotective, and cardioprotective properties. This demonstrates the relevance of the genus as a rich source of compounds with valuable therapeutic properties, with potential use in the prevention and treatment of nontransmissible chronic diseases.

Keywords: Clusiaceae; phytochemical compounds; therapeutic effects.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Bioactive compounds of Garcinia brasiliensis.
Figure 2
Figure 2
Bioactive compounds of Garcinia gardneriana.
Figure 3
Figure 3
Bioactive compounds of Garcinia pedunculata.
Figure 4
Figure 4
Bioactive compounds of Garcinia cambogia.
Figure 5
Figure 5
Bioactive compounds of Garcinia mangostana.
See this image and copyright information in PMC

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