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. 2021 Jun:63:104-105.
doi: 10.1016/j.jcrc.2020.09.009. Epub 2020 Sep 19.

Shortage of anesthetics: Think of inhaled sedation!

Affiliations

Shortage of anesthetics: Think of inhaled sedation!

N Ferrière et al. J Crit Care. 2021 Jun.
No abstract available

Keywords: Acute respiratory distress syndrome; Anesthetics; Inhalation; Isoflurane; SARS-Cov-2.

PubMed Disclaimer

Conflict of interest statement

Declaration of Competing Interest None to declare.

Figures

Fig. 1
Fig. 1
Sufentanyl consumption before and after volatile anesthetics introduction. The figure displays the Box-and-whisker plot of the sufentanyl consumption, before and after volatile anesthetics introduction while keeking the same sedation goal. Central grey box represents the values from the lower to upper quartile (25 to 75 percentile). The middle line represents the median. The horizontal line extends from the minimum to the maximal value, excluding outside and far out values. A P value equal or below 0.05 was considered statistically significant.
Supplementary Fig. S1
Supplementary Fig. S1
Nurse driven of inhaled sedation with Isoflurane protocol using Richmond Agitation-Sedation Scale (RASS) and expired fraction of Isoflurane (IsoEF).

References

    1. Choo E.K., Rajkumar S.V. Medication shortages during the COVID-19 crisis: what we must do. Mayo Clin Proc. 2020;95(6):1112–1115. doi: 10.1016/j.mayocp.2020.04.001. - DOI - PMC - PubMed
    1. Ranney M.L., Griffeth V., Ashish K.J. Critical supply shortages – the need for ventilator and personal protective equipment during the COVID-19 pandemic. New Engl J Med. 2020;382(18) doi: 10.1056/nejmp2006141. - DOI - PubMed
    1. L'Her E., Dy L., Pili R., Prat G., Tonnelier J.M., Lefevre M., et al. Feasibility and potential cost/benefit of routine isoflurane sedation using an anesthetic-conserving device: a prospective observational study. Respir Care. 2008;53(10):1295–1303. - PubMed
    1. Perbet S., Bourdeaux B., Sautou V., Pereira B., Chabanne R., Constantin J.M., et al. A pharmacokinetic study of 48-hour sevoflurane inhalation using a disposable delivery system (AnaConDa®) in ICU patients. Minerva Anestesiol. 2014;80(6):655–665. - PubMed
    1. Mesnil M., Capdevila X., Bringuier S., Trine P.O., Falquet Y., Charbit J., et al. Long-term sedation in intensive care unit: a randomized comparison between inhaled sevoflurane and intravenous propofol or midazolam. Intensive Care Med. 2011;37(6):933–941. doi: 10.1007/s00134-011-2187-3. - DOI - PubMed