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Comment
. 2020 Oct 5;11(1):4999.
doi: 10.1038/s41467-020-18856-0.

Reply to: "Does PCNA diffusion on DNA follow a rotation-coupled translation mechanism?"

Matteo De March  1 , Silvia Onesti  2 , Alfredo De Biasio  3
Affiliations
Comment

Reply to: "Does PCNA diffusion on DNA follow a rotation-coupled translation mechanism?"

Matteo De March et al. Nat Commun. .
No abstract available

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1. PCNA–DNA complexes OMIT maps.
a Two views of the composite OMIT map of the human PCNA–DNA complex (PDB-ID 6GIS) contoured at 0.9 σ showing the PCNA central channel. PCNA is shown as a ribbon, DNA as sticks. b Two views of the composite OMIT map of the yeast PCNA–DNA complex (PDB-ID 3K4X) contoured at 0.9 σ.
See this image and copyright information in PMC

Comment on

References

    1. De March M, et al. Structural basis of human PCNA sliding on DNA. Nat. Commun. 2017;8:13935. doi: 10.1038/ncomms13935. - DOI - PMC - PubMed
    1. Kochaniak AB, et al. Proliferating cell nuclear antigen uses two distinct modes to move along DNA. J. Biol. Chem. 2009;284:17700–17710. doi: 10.1074/jbc.M109.008706. - DOI - PMC - PubMed
    1. Murshudov GN, et al. REFMAC5 for the refinement of macromolecular crystal structures. Acta Crystallogr. D Biol. Crystallogr. 2011;67:355–367. doi: 10.1107/S0907444911001314. - DOI - PMC - PubMed
    1. McNally R, Bowman GD, Goedken ER, O’Donnell M, Kuriyan J. Analysis of the role of PCNA-DNA contacts during clamp loading. BMC Struct. Biol. 2010;10:3. doi: 10.1186/1472-6807-10-3. - DOI - PMC - PubMed
    1. Hammel M, et al. HU multimerization shift controls nucleoid compaction. Sci. Adv. 2016;2:e1600650. doi: 10.1126/sciadv.1600650. - DOI - PMC - PubMed

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