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. 2021 Mar;15(3):779-789.
doi: 10.1002/1878-0261.12812. Epub 2020 Oct 18.

Tackling the cancer burden: the economic impact of primary prevention policies

Jane Cheatley  1 , Alexandra Aldea  1 , Aliénor Lerouge  1 , Marion Devaux  1 , Sabine Vuik  1 , Michele Cecchini  1
Affiliations

Tackling the cancer burden: the economic impact of primary prevention policies

Jane Cheatley et al. Mol Oncol. 2021 Mar.

Abstract

Cancer is a noncommunicable disease (NCD) with increasing incidence and therefore constitutes a major public health issue. To reduce the health and economic burden of cancer, policy-makers across the world have implemented a range of preventative interventions targeting risk factors with a known link to the disease. In this article, we examine the impact of six primary prevention interventions - related to physical inactivity, unhealthy diet or harmful alcohol use - on cancer-related health outcomes and healthcare expenditure. Here, we used the OECD Strategic Public Health Planning for NCDs (SPHeP-NCDs) model to quantify outcomes and costs for each intervention for years 2020-2050 across 37 countries. Results from the model indicate that all interventions could lead to a reduction in the number of new cancer cases, in particular those targeting harmful alcohol consumption. Introducing an alcohol tax, for instance, is estimated to reduce related cancer cases by 5619 a year or 174 193 by 2050. A breakdown of results by type of cancer revealed interventions had the largest impact on colorectal cancer with, on average, 41 140 cases avoided per intervention by 2050. In proportional terms, interventions had the greatest impact on new oesophageal and liver cancers. Findings from this article are designed to assist decision-makers efficiently allocate limited resources to meet public health objectives.

Keywords: alcohol; cancer; healthcare expenditure; noncommunicable diseases; obesity; projection.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1
Fig. 1
New cancer cases avoided over time by intervention (2020–2050). Shaded areas represent 95% CI. Source: OECD SPHeP‐NCD model, 2020.
Fig. 2
Fig. 2
New cancer cases avoided by type of cancer and intervention by 2050. Vertical black lines represent 95% CI. Source: OECD SPHeP‐NCD model, 2020.
Fig. 3
Fig. 3
New cancer cases avoided by age, gender and intervention by 2050. Vertical black lines represent 95% CI. Source: OECD SPHeP‐NCD model, 2020.
Fig. 4
Fig. 4
Impact on cancer‐related health expenditure by intervention and country, per capita, per year (USD PPP) (2020–2050). Vertical black lines represent 95% CI. Source: OECD SPHeP‐NCD model, 2020.
See this image and copyright information in PMC

References

    1. International Agency for Research on Cancer (2018) All cancers. Available at https://gco.iarc.fr/today/data/factsheets/cancers/39‐All‐cancers‐fact‐sh...
    1. International Agency for Research on Cancer (2018) Estimated age‐standardized incidence rates (World) in 2018, all cancers, females, all ages.
    1. International Agency for Research on Cancer (2018) Estimated age‐standardized incidence rates (World) in 2018, all cancers, males, all ages.
    1. International Agency for Research on Cancer (2018) Estimated age‐standardized incidence rates (World) in 2018, worldwide, females, all ages.
    1. International Agency for Research on Cancer (2018) Estimated age‐standardized incidence rates (World) in 2018, worldwide, males, all ages.

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