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Review
. 2021 Mar 1;38(3):586-667.
doi: 10.1039/d0np00051e. Epub 2020 Oct 6.

The chemistry and biology of guanidine secondary metabolites

Roberto G S Berlinck  1 , Darlon I Bernardi, Taicia Fill, Alessandra A G Fernandes, Igor D Jurberg
Affiliations
Review

The chemistry and biology of guanidine secondary metabolites

Roberto G S Berlinck et al. Nat Prod Rep. .

Abstract

Covering: 2017-2019Guanidine natural products isolated from microorganisms, marine invertebrates and terrestrial plants, amphibians and spiders, represented by non-ribosomal peptides, guanidine-bearing polyketides, alkaloids, terpenoids and shikimic acid derived, are the subject of this review. The topics include the discovery of new metabolites, total synthesis of natural guanidine compounds, biological activity and mechanism-of-action, biosynthesis and ecological functions.

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