Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Nov;26(11):2163-2169.
doi: 10.1111/tbj.14069. Epub 2020 Oct 6.

Incidence, clinical features, and outcomes of special types in breast cancer in a single institution population

A M Moorman  1 , R Vink  2 , E J Th Rutgers  3 , E A Kouwenhoven  1
Affiliations

Incidence, clinical features, and outcomes of special types in breast cancer in a single institution population

A M Moorman et al. Breast J. 2020 Nov.

Abstract

The low incidence of special types of breast cancer hinders adequate clinical research efforts. As such, collecting sufficient data to develop well-established therapy strategies are difficult. The aim of our study was to obtain more data on these special types in order to better understand the different characteristics and optimize therapy strategies. A single-institution retrospective cohort study from January 2007 until September 2015. One hundred and five patients remained after excluding the patients with invasive ductal and lobular carcinoma. The percentage of these so called special types in this population was 4%. Tubular carcinoma, cribriform carcinoma, carcinoma with medullary features, carcinoma with apocrine differentiation, secretory carcinoma, mucinous carcinoma, and invasive papillary carcinoma had a good or excellent prognosis, while invasive micropapillary carcinoma, adenoid cystic carcinoma, metaplastic carcinoma, and carcinoma with neuroendocrine features had a worse prognosis. Special types of breast cancer form a heterogeneous group. Submitting them all to the same treatment modality may lead to both over- and under-treatment. We need to combine our data to optimize treatment strategies for the different special types.

Keywords: breast cancer; prognosis; rare; special types; treatment.

PubMed Disclaimer

References

REFERENCES

    1. WHO Classification of Tumours Editorial Board., International Agency for Research on Cancer., World Health Organization. WHO classification of tumours. Breast tumours. Lyon, France: International Agency for Research on Cancer.
    1. NABON BREAST CANCER AUDIT (NBCA) JAARVERSLAG 2017. 2018.
    1. Curigliano G, Burstein HJ, Winer EP, et al. De-escalating and escalating treatments for early-stage breast cancer: the St. Gallen international expert consensus conference on the primary therapy of early breast cancer 2017. Ann Oncol. 2019;30(7):1181.
    1. Sinn HP, Kreipe H. A brief overview of the WHO classification of breast tumors, 4th edition, focusing on issues and updates from the 3rd edition. Breast Care. 2013;8(2):149-154.
    1. Kader HA, Jackson J, Mates D, Andersen S, Hayes M, Olivotto IA. Tubular carcinoma of the breast: a population-based study of nodal metastases at presentation and of patterns of relapse. Breast J. 2001;7(1), 8-13. http://www.ncbi.nlm.nih.gov/pubmed/11348409. Accessed September 15, 2019.

LinkOut - more resources