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. 2020 Nov:212:112044.
doi: 10.1016/j.jphotobiol.2020.112044. Epub 2020 Sep 28.

UV-LED disinfection of Coronavirus: Wavelength effect

Yoram Gerchman  1 , Hadas Mamane  2 , Nehemya Friedman  3 , Michal Mandelboim  3
Affiliations

UV-LED disinfection of Coronavirus: Wavelength effect

Yoram Gerchman et al. J Photochem Photobiol B. 2020 Nov.

Erratum in

Abstract

UV light-emitting diodes (UV LEDs) are an emerging technology and a UV source for pathogen inactivation, however low UV-LED wavelengths are costly and have low fluence rate. Our results suggest that the sensitivity of human Coronavirus (HCoV-OC43 used as SARS-CoV-2 surrogate) was wavelength dependent with 267 nm ~ 279 nm > 286 nm > 297 nm. Other viruses showed similar results, suggesting UV LED with peak emission at ~286 nm could serve as an effective tool in the fight against human Coronaviruses.

Keywords: COVID19; Corona; Coronavirus; SARS; UV-LEDs; Wavelength.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Unlabelled Image
Graphical abstract
Fig. 1
Fig. 1
Emission spectra of UV LEDs used in this study.
Fig. 2
Fig. 2
Schematic layout of the inactivation experiment with the 24-well plate used in this study. Numbers in wells represent the incident irradiance (mW/cm2) as measured for each particular well location (Top-left, 267 nm; top-right, 279 nm; bottom-left, 286 nm; bottom-right, 297 nn). The red encircle irradiation area for one time/dose irradiation point (left: 4-well column, for 267/286 nm rectangular system; right: 2 × 2 wells for 279/297 nm round system). (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)
Fig. 3
Fig. 3
Dose (fluence) response curve of the HCoV-OC43 to UV-LEDs. N is virus count after the designated irradiation and N0 at time zero (without irradiation).
See this image and copyright information in PMC

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