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Comment
. 2021 Jan;19(1):5-6.
doi: 10.1038/s41579-020-00469-5.

Nanomaterials arising amid antibiotic resistance

Weiwei Gao  1 , Liangfang Zhang  2
Affiliations
Comment

Nanomaterials arising amid antibiotic resistance

Weiwei Gao et al. Nat Rev Microbiol. 2021 Jan.

Abstract

The rapid emergence of antibiotic resistance is recognized as a major public health threat. Nanomaterials have risen to tackle this problem through either improving the potency of existing antibiotics or generating entirely new antibacterial mechanisms.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1. Nanomaterials have major potential for treating antibiotic-resistant bacterial infections.
One emerging area is standalone ‘nano-objects’ that either improve the potency of antibiotics or confer bactericidal activity without using antibiotics. Another emerging area is nanostructured surfaces that prevent bacterial attachment or kill those attached bacteria through physico-mechanical interactions with the bacteria.
See this image and copyright information in PMC

Comment on

References

    1. Lesho EP, Laguio-Vila M. The slow-motion catastrophe of antimicrobial resistance and practical interventions for all prescribers. Mayo Clin. Proc. 2019;94:1040–1047. doi: 10.1016/j.mayocp.2018.11.005. - DOI - PubMed
    1. Dodds DR. Antibiotic resistance: A current epilogue. Biochem. Pharmacol. 2017;134:139–146. doi: 10.1016/j.bcp.2016.12.005. - DOI - PubMed
    1. Nathan C. Antibiotics at the crossroads. Nature. 2004;431:899–902. doi: 10.1038/431899a. - DOI - PubMed
    1. Cox E, Nambiar S, Baden L. Needed: antimicrobial development. New Engl. J. Med. 2019;380:783–785. doi: 10.1056/NEJMe1901525. - DOI - PubMed
    1. Blair JMA, Webber MA, Baylay AJ, Ogbolu DO, Piddock LJV. Molecular mechanisms of antibiotic resistance. Nat. Rev. Microbiol. 2015;13:42–51. doi: 10.1038/nrmicro3380. - DOI - PubMed

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