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Review
. 2021 Jan;36(1):22-25.
doi: 10.1097/HCO.0000000000000802.

Cryoballoon ablation for extrapulmonary vein targets

Affiliations
Review

Cryoballoon ablation for extrapulmonary vein targets

Tian-You Ling et al. Curr Opin Cardiol. 2021 Jan.

Abstract

Purpose of review: Cryoballoon catheter can create large and contiguous lesions with stable contact during ablation. It has proven to be well tolerated and effective in pulmonary vein isolation. But atrial arrhythmias, including atrial fibrillation, atrial tachycardia, and atrial flutter (AFL), also relate to many extrapulmonary vein targets. It is necessary to understand the current evidence for the use of cryoballoon ablation for targets outside of pulmonary veins.

Recent findings: Studies have shown that the cryoballoon ablation can be used in extrapulmonary vein area, including left atrium roof, left atrial appendages, posterior left atrial wall, mitral isthmus, and right atrial appendage. The results indicate cryoballoon ablation is an effective and well-tolerated treatment option for the atrial arrhythmias in these locations outside of pulmonary vein when clinical necessary.

Summary: The cryoballoon ablation can safely and effectively perform contiguous linear lesions, structure isolations, and local ablation for targets outside of the pulmonary veins.

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References

    1. Calkins H, Hindricks G, Cappato R, et al. 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation. Europace 2018; 20:e1–e160.
    1. Wu L, Huang C, Huang D, et al. Cryoballoon ablation of atrial fibrillation: consensus of Chinese experts. Chin J Cardiac Arrhythmias 2020; 24:96–112.
    1. Su WW, Alzubaidi M, Tseng R, et al. Novel usage of the cryoballoon catheter to achieve large area atrial substrate modification in persistent and long-standing persistent atrial fibrillation. J Interv Card Electrophysiol 2016; 46:275–285.
    1. Akkaya E, Berkowitsch A, Rieth A, et al. Clinical outcome and left atrial function after left atrial roof ablation using the cryoballoon technique in patients with symptomatic persistent atrial fibrillation. Int J Cardiol 2019; 292:112–118.
    1. Kuniss M, Akkaya E, Berkowitsch A, et al. Left atrial roof ablation in patients with persistent atrial fibrillation using the second-generation cryoballoon: benefit or wasted time? Clin Res Cardiol 2020; 109:714–724.

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