Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 May;42(5):604-608.
doi: 10.1017/ice.2020.1244. Epub 2020 Oct 8.

Prevalence of SARS-CoV-2 antibodies among Swiss hospital workers: Results of a prospective cohort study

Affiliations

Prevalence of SARS-CoV-2 antibodies among Swiss hospital workers: Results of a prospective cohort study

Philipp P Kohler et al. Infect Control Hosp Epidemiol. 2021 May.

Abstract

In this prospective cohort of 1,012 Swiss hospital employees, 3 different assays were used to screen serum for SARS-CoV-2 antibodies. Seropositivity was 1%; the positive predictive values of the lateral-flow immunoassay were 64% (IgG) and 13% (IgM). History of fever and myalgia most effectively differentiated seropositive and seronegative participants.

PubMed Disclaimer

Conflict of interest statement

All authors report no conflicts of interest relevant to this article.

Figures

Fig. 1.
Fig. 1.
Results from baseline serology testing (n = 1,012) and from 4-week follow-up (n = 58). Cases with discrepant results between baseline and follow-up are highlighted with arrows.

References

    1. Adams JG, Walls RM. Supporting the health care workforce during the COVID-19 global epidemic. JAMA 2020;323:1439–1440. - PubMed
    1. Chirico F, Nucera G, Magnavita N. COVID-19: protecting healthcare workers is a priority. Infect Control Hosp Epidemiol 2020. doi: 10.1017/ice.2020.148. - DOI - PMC - PubMed
    1. Mizumoto K, Kagaya K, Zarebski A, Chowell G. Estimating the asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases on board the Diamond Princess cruise ship, Yokohama, Japan, 2020. Euro Surveill 2020;25(10): 2000180. - PMC - PubMed
    1. Woloshin S, Patel N, Kesselheim AS. False negative tests for SARS-CoV-2 infection—challenges and implications. N Engl J Med 2020;383(6):e38. - PubMed
    1. Weinstein MC, Freedberg KA, Hyle EP, Paltiel AD. Waiting for certainty on COVID-19 antibody tests—at what cost? N Engl J Med 2020;383(6):e37. - PubMed

Publication types