Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Aug;199(8):3159-3176.
doi: 10.1007/s12011-020-02414-2. Epub 2020 Oct 7.

Metal Nanoparticles: a Promising Treatment for Viral and Arboviral Infections

Kaminee Maduray  1 , Raveen Parboosing  2
Affiliations
Review

Metal Nanoparticles: a Promising Treatment for Viral and Arboviral Infections

Kaminee Maduray et al. Biol Trace Elem Res. 2021 Aug.

Abstract

Globally, viral diseases continue to pose a significant threat to public health. Recent outbreaks, such as influenza, coronavirus, Ebola, and dengue, have emphasized the urgent need for new antiviral therapeutics. Considerable efforts have focused on developing metal nanoparticles for the treatment of several pathogenic viruses. As a result of these efforts, metal nanoparticles are demonstrating promising antiviral activity against pathogenic surrogates and clinical isolates. This review summarizes the application of metal nanoparticles for the treatment of viral infections. It provides information on synthesis methods, size-related properties, nano-bio-interaction, and immunological effects of metal nanoparticles. This article also addresses critical criteria and considerations for developing clinically translatable nanosized metal particles to treat viral diseases.

Keywords: Arbovirus; Metal nanoparticle; Nanotechnology; Nanotherapeutics; Treatment; Virus.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no conflict of interest.

References

    1. Aderibigbe BA. Metal-based nanoparticles for the treatment of infectious diseases. Molecules. 2017;22(8):1370. - PMC - PubMed
    1. Joob B, Wiwanitkit V. Nanotechnology for health: A new useful technology in medicine. Medi J Dr DY Patil Univ. 2017;10(5):401.
    1. Prasad M, Lambe UP, Brar B, Shah I, J M, Ranjan K, Rao R, Kumar S, Mahant S, Khurana SK, Iqbal HMN, Dhama K, Misri J, Prasad G. Nanotherapeutics: an insight into healthcare and multi-dimensional applications in medical sector of the modern world. Biomed Pharmacother. 2018;97:1521–1537. - PubMed
    1. Nikalje AP. Nanotechnology and its applications in medicine. Med Chem. 2015;5(2):081–089.
    1. Anselmo AC, Mitragotri S. Nanoparticles in the clinic. Bioeng Translat Med. 2016;1(1):10–29. - PMC - PubMed