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. 2021 Mar;73(3):542-543.
doi: 10.1002/art.41550. Epub 2021 Jan 27.

Trends in Utilization of Urate-Lowering Therapies Following the US Food and Drug Administration's Boxed Warning on Febuxostat

Seoyoung C Kim  1 , Tuhina Neogi  1 , Erin Kim  1 , Joyce Lii  1 , Rishi J Desai  1
Affiliations

Trends in Utilization of Urate-Lowering Therapies Following the US Food and Drug Administration's Boxed Warning on Febuxostat

Seoyoung C Kim et al. Arthritis Rheumatol. 2021 Mar.
No abstract available

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Conflict of interest statement

Potential Conflict of Interest: SCK receives research grants to the Brigham and Women’s Hospital from Pfizer, AbbVie, Roche, and Bristol-Myers Squibb for unrelated studies. RJD reports receiving research grants to the Brigham and Women’s Hospital from Novartis, Bayer, and Vertex for unrelated studies. TN is supported by NIH K24AR070892. EK and JL have nothing to disclose.

Figures

Figure.
Figure.
2009 and 2019 (top) and quarterly number of ULT users per 1,000 gout patients between 2009 and 2019 (bottom).
See this image and copyright information in PMC

References

    1. Chen-Xu M, Yokose C, Rai SK, Pillinger MH, Choi HK. Contemporary Prevalence of Gout and Hyperuricemia in the United States and Decadal Trends: The National Health and Nutrition Examination Survey, 2007–2016. Arthritis Rheumatol. 2019;71(6):991–999. - PMC - PubMed
    1. FitzGerald JD, Dalbeth N, Mikuls T, et al. 2020 American College of Rheumatology Guideline for the Management of Gout. Arthritis Rheumatol. 2020;72(6):879–895. - PubMed
    1. White WB, Saag KG, Becker MA, et al. Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout. N Engl J Med. 2018;378(13):1200–1210. - PubMed
    1. FDA U. FDA adds Boxed Warning for increased risk of death with gout medicine Uloric (febuxostat). FDA Drug Safety Podcast Web site. https://www.fda.gov/drugs/fda-drug-safety-podcasts/fda-adds-boxed-warnin.... Published 2019. Accessed August 5, 2020.

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