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. 2021 Aug 14;45(7):e1-e3.
doi: 10.1093/jat/bkaa145.

Severe Neurological Sequelae after a Recreational Dose of LSD

Affiliations

Severe Neurological Sequelae after a Recreational Dose of LSD

Rachel Aakerøy et al. J Anal Toxicol. .

Abstract

A young man with an unremarkable medical history suffered a seizure with subsequent cardiorespiratory arrest and severe neurological sequelae after ingesting a blotter. Analysis of a similar blotter and a serum sample obtained 3 h after the event detected lysergic acid diethylamide (LSD) at an amount of 300 µg in the blotter and at a concentration of 4.0 ng/mL (12.4 nmol/L) in the serum. No other drugs were present in concentrations which may confer significant effects. In addition, no individual traits which would make the patient particularly susceptible to adverse LSD effects have subsequently been identified. This suggests that LSD may confer toxic effects in previously healthy individuals.

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References

    1. KRIPOS . Narkotika og dopingstatistikk. (2019) https://www.politiet.no/globalassets/04-aktuelt-tall-og-fakta/narkotika/... (Accessed August 13, 2020).
    1. Nichols D.E., Grob C.S. (2018) Is LSD toxic?. Forensic Science International, 284, 141–145. doi: 10.1016/j.forsciint.2018.01.006 - DOI - PubMed
    1. Carbonaro T.M., Gatsch M.B. (2016) Neuropharmacology of N,N-dimethyltryptamine. Brain Research Bulletin, 126, 74–88. doi: 10.1016/j.brainresbull.2016.04.016 - DOI - PMC - PubMed
    1. Vindenes V., Jordbru D., Knapskog A.B., Kvan E., Mathisrud G., Slørdal L., et al. (2012) Impairment based legislative limits for driving under the influence of non-alcohol drugs in Norway. Forensic Science International, 219, 1–11. doi: 10.1016/j.forsciint.2011.11.004 - DOI - PubMed
    1. Nyberg Karlsen S., Spigset O., Slørdal L. (2008) The dark side of ecstasy: Neuropsychiatric symptoms after exposure to 3,4-methylenedioxymethamphetamine. Basic and Clinical Pharmacology and Toxicology, 102, 15–24. doi: 10.1111/j.1742-7843.2007.00159.x - DOI - PubMed