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Comment
. 2020 Aug;131(2):e83-e84.
doi: 10.1213/ANE.0000000000004885.

Fibrinogen Concentrate Compared to Cryoprecipitate to Reduce Transfusion in Infants Undergoing Cardiac Surgery: How Confident Can We Be?

Hilary P Grocott  1 , Philip M Jones  2
Affiliations
Comment

Fibrinogen Concentrate Compared to Cryoprecipitate to Reduce Transfusion in Infants Undergoing Cardiac Surgery: How Confident Can We Be?

Hilary P Grocott et al. Anesth Analg. 2020 Aug.
No abstract available

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Comment in

  • In Response.
    Downey LA, Guzzetta NA. Downey LA, et al. Anesth Analg. 2020 Aug;131(2):e84-e86. doi: 10.1213/ANE.0000000000004886. Anesth Analg. 2020. PMID: 33031679 No abstract available.

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References

    1. Downey LA, Andrews J, Hedlin H, et al.Fibrinogen concentrate as an alternative to cryoprecipitate in a postcardiopulmonary transfusion algorithm in infants undergoing cardiac surgery: a prospective randomized controlled trial. Anesth Analg. 2020;130:740–751.
    1. Callum J, Farkouh ME, Scales DC, et al.Effect of fibrinogen concentrate vs cryoprecipitate on blood component transfusion after cardiac surgery: the FIBRES randomized clinical trial. JAMA. 2019;322:1966–1976.
    1. Downey LA, Williams GDRepurposing of fibrinogen concentrate as a cost-effective and safe hemostatic agent in infants undergoing cardiac surgery on cardiopulmonary bypass. Available at: https://clinicaltrials.gov/ProvidedDocs/00/NCT03014700/Prot_000.pdf. Accessed May 11, 2020.
    1. Kahan BC, Morris TPAnalysis of multicentre trials with continuous outcomes: when and how should we account for centre effects? Stat Med. 2013;32:1136–1149.
    1. Jones PM, Bryson GLOpen season: positive changes for increased transparency in the biomedical literature. Can J Anaesth. 2018;65:246–253.