Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Oct;146(4):685-693.
doi: 10.1016/j.jaci.2020.08.011.

Obesity and asthma

Sarah Miethe  1 , Antonina Karsonova  2 , Alexander Karaulov  2 , Harald Renz  3
Affiliations
Review

Obesity and asthma

Sarah Miethe et al. J Allergy Clin Immunol. 2020 Oct.

Abstract

Obesity has been well recognized as an important comorbidity in patients with asthma, representing a unique phenotype and endotype. This association indicates a close relationship between metabolic and inflammatory dysregulation. However, the detailed organ-organ, cellular, and molecular interactions are not completely resolved. Because of that, the relationship between obesity and asthma remains unclear. In this article, clinical and epidemiological studies, as well as data from experimental animal work, are being summarized to provide a state of the art update on this important topic. Much more work is needed, particularly mechanistic, to fully understand the interaction between obesity and asthma and to develop novel preventive and therapeutic strategies.

Keywords: Asthma; metabolism; obesity.

PubMed Disclaimer

Publication types