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. 2021 Feb 17;57(2):2002524.
doi: 10.1183/13993003.02524-2020. Print 2021 Feb.

Continuous positive airway pressure in COVID-19 patients with moderate-to-severe respiratory failure

Collaborators, Affiliations

Continuous positive airway pressure in COVID-19 patients with moderate-to-severe respiratory failure

Claudia Brusasco et al. Eur Respir J. .

Abstract

CPAP can be successfully used in a number of COVID-19 patients with hypoxaemic respiratory failure and gas exchange and radiological findings similar to those generally considered to be indications for invasive mechanical ventilation https://bit.ly/2GpBx6a

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Conflict of interest statement

Conflict of interest: C. Brusasco has nothing to disclose. Conflict of interest: F. Corradi has nothing to disclose. Conflict of interest: A. Di Domenico has nothing to disclose. Conflict of interest: F. Raggi has nothing to disclose. Conflict of interest: G. Timossi has nothing to disclose. Conflict of interest: G. Santori has nothing to disclose. Conflict of interest: V. Brusasco has nothing to disclose.

Figures

FIGURE 1
FIGURE 1
a) Algorithm for respiratory support given to coronavirus disease 2019 (COVID-19) patients. BF: breathing frequency; ABG: arterial blood gas; SpO2: oxygen saturation measured by pulse oximetry; PaO2/FIO2: arterial oxygen tension/inspiratory oxygen fraction ratio; PaCO2: arterial carbon dioxide tension; SBP: systolic blood pressure; DBP: diastolic blood pressure; HR: heart rate; CPAP: continuous positive airway pressure; PEEP: positive end-expiratory pressure; IMV: invasive mechanical ventilation; ICU: intensive care unit. b) Study diagram. ER: emergency room. c, d) Scatterplots of individual values of computed tomography estimated c) lung weight and c) PaO2/FIO2, with medians and interquartile ranges.

Comment in

References

    1. Rochwerg B, Brochard L, Elliott MW, et al. . Official ERS/ATS clinical practice guidelines: noninvasive ventilation for acute respiratory failure. Eur Respir J 2017; 50: 1602426. doi:10.1183/13993003.02426-2016 - DOI - PubMed
    1. Vitacca M, Nava S, Santus P, et al. . Early consensus management for non-ICU ARF SARS-CoV-2 emergency in Italy: from ward to trenches. Eur Respir J 2020; 55: 2000632. doi:10.1183/13993003.00632-2020 - DOI - PMC - PubMed
    1. Grasselli G, Zangrillo A, Zanella A, et al. . Baseline Characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy Region, Italy. JAMA 2020; 323: 1574–1581. doi:10.1001/jama.2020.5394 - DOI - PMC - PubMed
    1. Bhatraju PK, Ghassemieh BJ, Nichols M, et al. . Covid-19 in critically ill patients in the Seattle region - case series. N Engl J Med 2020; 382: 2012–2022. doi:10.1056/NEJMoa2004500 - DOI - PMC - PubMed
    1. Yang X, Yu Y, Xu J, et al. . Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. Lancet Respir Med 2020; 8: 475–481. doi:10.1016/S2213-2600(20)30079-5 - DOI - PMC - PubMed

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