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. 2021 Feb 17;57(2):2002524.
doi: 10.1183/13993003.02524-2020. Print 2021 Feb.

Continuous positive airway pressure in COVID-19 patients with moderate-to-severe respiratory failure

Claudia Brusasco  1 , Francesco Corradi  1   2 , Antonia Di Domenico  3 , Francesca Raggi  4 , Graziano Timossi  4 , Gregorio Santori  5 , Vito Brusasco  6 ; Galliera CPAP-Covid-19 study group; collaborators of the Galliera CPAP-COVID-19 study group are
Collaborators, Affiliations

Continuous positive airway pressure in COVID-19 patients with moderate-to-severe respiratory failure

Claudia Brusasco et al. Eur Respir J. .

Abstract

CPAP can be successfully used in a number of COVID-19 patients with hypoxaemic respiratory failure and gas exchange and radiological findings similar to those generally considered to be indications for invasive mechanical ventilation https://bit.ly/2GpBx6a

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Conflict of interest statement

Conflict of interest: C. Brusasco has nothing to disclose. Conflict of interest: F. Corradi has nothing to disclose. Conflict of interest: A. Di Domenico has nothing to disclose. Conflict of interest: F. Raggi has nothing to disclose. Conflict of interest: G. Timossi has nothing to disclose. Conflict of interest: G. Santori has nothing to disclose. Conflict of interest: V. Brusasco has nothing to disclose.

Figures

FIGURE 1
FIGURE 1
a) Algorithm for respiratory support given to coronavirus disease 2019 (COVID-19) patients. BF: breathing frequency; ABG: arterial blood gas; SpO2: oxygen saturation measured by pulse oximetry; PaO2/FIO2: arterial oxygen tension/inspiratory oxygen fraction ratio; PaCO2: arterial carbon dioxide tension; SBP: systolic blood pressure; DBP: diastolic blood pressure; HR: heart rate; CPAP: continuous positive airway pressure; PEEP: positive end-expiratory pressure; IMV: invasive mechanical ventilation; ICU: intensive care unit. b) Study diagram. ER: emergency room. c, d) Scatterplots of individual values of computed tomography estimated c) lung weight and c) PaO2/FIO2, with medians and interquartile ranges.
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