Pancreatitis and Acute Liver Failure From Coricidin® HBP Intoxication
- PMID: 33033679
- PMCID: PMC7532876
- DOI: 10.7759/cureus.10202
Pancreatitis and Acute Liver Failure From Coricidin® HBP Intoxication
Abstract
The use of over-the-counter medications as recreational drugs of abuse in adolescents is increasing. We present the case of a patient who presented with abdominal pain after the ingestion of Coricidin®, an over-the-counter cold medication that contains acetaminophen, chlorpheniramine maleate, and dextromethorphan hydrobromide. The case was complicated by acute liver failure and concomitant pancreatitis that, in a few reported cases, has been associated with high doses of acetaminophen.
Keywords: inpatient pediatrics; liver failure; overdose; toxicology.
Copyright © 2020, Medows et al.
Conflict of interest statement
The authors have declared that no competing interests exist.
Similar articles
-
A possible trend suggesting increased abuse from Coricidin exposures reported to the Texas Poison Network: comparing 1998 to 1999.Vet Hum Toxicol. 2002 Jun;44(3):169-71. Vet Hum Toxicol. 2002. PMID: 12046973
-
Coricidin HBP abuse: patient characteristics and psychiatric manifestations as recorded in an inpatient psychiatric unit.J Addict Dis. 2008;27(1):25-32. doi: 10.1300/J069v27n01_03. J Addict Dis. 2008. PMID: 18551885
-
Serotonin syndrome in dextromethorphan ingestion responsive to propofol therapy.Pediatr Emerg Care. 2007 Nov;23(11):829-31. doi: 10.1097/PEC.0b013e31815a0667. Pediatr Emerg Care. 2007. PMID: 18007217
-
Adolescent abuse of dextromethorphan.Clin Pediatr (Phila). 2005 Sep;44(7):565-8. doi: 10.1177/000992280504400702. Clin Pediatr (Phila). 2005. PMID: 16151560 Review.
-
Abuse of over-the-counter dextromethorphan by teenagers.South Med J. 1993 Oct;86(10):1151-3. doi: 10.1097/00007611-199310000-00014. South Med J. 1993. PMID: 8211334 Review.
Cited by
-
Focus on Over-the-Counter Drugs' Misuse: A Systematic Review on Antihistamines, Cough Medicines, and Decongestants.Front Psychiatry. 2021 May 7;12:657397. doi: 10.3389/fpsyt.2021.657397. eCollection 2021. Front Psychiatry. 2021. PMID: 34025478 Free PMC article.
-
Two rare pancreatic parenchymal hemorrhagic lesions associated with acute pancreatitis in acute liver failure: a case report and literature review.Clin J Gastroenterol. 2023 Apr;16(2):254-262. doi: 10.1007/s12328-022-01738-x. Epub 2022 Nov 30. Clin J Gastroenterol. 2023. PMID: 36449216 Review.
References
-
- Drug-induced acute pancreatitis in adults: an update. Simons-Linares CR, Elkhouly MA, Salazar MJ. Pancreas. 2019;48:1263–1273. - PubMed
-
- The abuse of dextromethorphan-based cough syrup: a pilot study of the community of Waynesboro, Pennsylvania. Darboe MN, Keenan GR Jr, Richards TK. https://pubmed.ncbi.nlm.nih.gov/8874609/ Adolescence. 1996;31:633–644. - PubMed
-
- Prescription medication sharing among adolescents: prevalence, risks, and outcomes. Goldsworthy RC, Mayhorn CB. J Adolesc Health. 2009;45:634–637. - PubMed
-
- Drug-induced acute pancreatitis: a review. Jones MR, Hall OM, Kaye AM, Kaye AD. https://pubmed.ncbi.nlm.nih.gov/25829880/ Ochsner J. 2015;15:45–51. - PMC - PubMed
Publication types
LinkOut - more resources
Full Text Sources
Miscellaneous