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Review
. 2021 Mar;53(2):51-54.
doi: 10.23822/EurAnnACI.1764-1489.173. Epub 2021 Mar 1.

Urticaria and coronavirus infection: a lesson from SARS-CoV-2 pandemic

A Allegra  1   2 , R Asero  3 , A Giovannetti  4 , S Isola  2   5 , S Gangemi  5
Affiliations
Free article
Review

Urticaria and coronavirus infection: a lesson from SARS-CoV-2 pandemic

A Allegra et al. Eur Ann Allergy Clin Immunol. 2021 Mar.
Free article

Abstract

Urticaria is a condition involving both skin and mucosal tissues characterized by the presence of wheals and/or angioedema. The acute form has been related to allergic reactions to drugs or foods, interaction with chemicals, or infections. We reviewed the association of urticaria with coronavirus infections. This review was carried out by the use of two search engines for published original articles, employing two key terms correlated to urticaria and viruses: "urticaria" and one term linked to each virus. The research of the relationships between SARS-CoV-2 and urticaria produced 18 papers (including a total of 114 cases). Surprisingly, the search for cases of urticaria in patients with SARS-CoV or MERS produced no results. We tried to interpret this discrepancy and attempted to analyze the possible pathogenesis of urticaria lesions in SARS-CoV-2.

Keywords: Allergy; COVID-19; MERS-CoV; SARS-CoV; SARS-CoV-2; Urticaria; viral infection.

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