Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Oct 9;295(41):13994-13995.
doi: 10.1074/jbc.CL120.015923.

When Taxol met tubulin

John Arnst
Review

When Taxol met tubulin

John Arnst. J Biol Chem. .
No abstract available

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Strands of tubulin, a protein in the cell's skeleton, photographed using a high-resolution microscopy technique. Image made by Pakorn Kanchanawong (National University of Singapore) and Clare Waterman (NHLBI, National Institutes of Health).
See this image and copyright information in PMC

References

    1. Kumar N. (1981) Taxol-induced polymerization of purified tubulin. J. Biol. Chem. 256, 10435–10441 - PubMed
    1. Cragg G. M., Boyd M. R., Cardellina J. H., Newman D. J., Snader K. M., and McCloud T. G. (1994) Ethnobotany and drug discovery: the experience of the US National Cancer Institute. Ciba Found. Symp. 185, 178–190 10.1002/9780470514634.ch13 - DOI - PubMed
    1. Wani M. C., Taylor H. L., Wall M. E., Coggon P., and McPhail A. T. (1971) Plant antitumor agents. VI. Isolation and structure of Taxol, a novel antileukemic and antitumor agent from Taxus brevifolia. J. Am. Chem. Soc. 93, 2325–2327 10.1021/ja00738a045 - DOI - PubMed
    1. Schiff P. B., Fant J., and Horwitz S. B. (1979) Promotion of microtubule assembly in vitro by Taxol. Nature 277, 665–667 10.1038/277665a0 - DOI - PubMed
    1. Fischer R. S., and Fowler V. M. (2015) The state of the cytoskeleton in 2015. J. Biol. Chem. 290, 17133–17136 10.1074/jbc.R115.663716 - DOI - PMC - PubMed