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Comment
. 2021 Jan;127(1):35-36.
doi: 10.1111/bju.15267. Epub 2020 Oct 24.

Novel use of an old compound? Urologist-led Bacille Calmette-Guérin vaccine trials in the prevention of coronavirus disease 2019

Alexandre R Zlotta  1   2
Affiliations
Comment

Novel use of an old compound? Urologist-led Bacille Calmette-Guérin vaccine trials in the prevention of coronavirus disease 2019

Alexandre R Zlotta. BJU Int. 2021 Jan.
No abstract available

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Conflict of interest statement

Dr Alexandre Zlotta, is the Principal Investigator of ‘Efficacy and Safety of VPM1002 in Reducing SARS‐CoV‐2 (COVID‐19) Infection Rate and Severity, NCT04439045’ one of the trials mentioned in the submitted work. Dr Alexandre Zlotta, is a consultant for Verity Pharmaceuticals, the Canadian importer of VPM1002.

Comment on

References

    1. Mantovani A, Netea MG. Trained innate immunity, epigenetics, and Covid‐19. N Engl J Med 2020; 383: 1078–80 - PubMed
    1. Giamarellos‐Bourboulis EJ, Tsilika M, Moorlag S et al. Activate: randomized clinical trial of BCG vaccination against infection in the elderly. Cell 2020. [Epub ahead of print]. 10.1016/j.cell.2020.08.051 - DOI - PMC - PubMed
    1. Hegarty PK, Sfakianos JP, Giannarini G, DiNardo AR, Kamat AM. COVID‐19 and bacillus Calmette‐Guérin: what is the link? Eur Urol Oncol 2020; 3: 259–61 - PMC - PubMed
    1. Netea MG, Giamarellos‐Bourboulis EJ, Domínguez‐Andrés J et al. Trained immunity: a tool for reducing susceptibility to and the severity of SARS‐CoV‐2 infection. Cell 2020; 181: 969–77 - PMC - PubMed
    1. Nieuwenhuizen NE, Kulkarni PS, Shaligram U et al. The recombinant bacille Calmette‐Guérin vaccine VPM1002: ready for clinical efficacy testing. Front Immunol 2017; 8: 1147 - PMC - PubMed