Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021:48:173-196.
doi: 10.1007/7854_2020_174.

Neuroanatomic and Functional Neuroimaging Findings

Affiliations

Neuroanatomic and Functional Neuroimaging Findings

Alexandre Paim Diaz et al. Curr Top Behav Neurosci. 2021.

Abstract

The search for brain morphology findings that could explain behavioral disorders has gone through a long path in the history of psychiatry. With the advance of brain imaging technology, studies have been able to identify brain morphology and neural circuits associated with the pathophysiology of mental illnesses, such as bipolar disorders (BD). Promising results have also shown the potential of neuroimaging findings in the identification of outcome predictors and response to treatment among patients with BD. In this chapter, we present brain imaging structural and functional findings associated with BD, as well as their hypothesized relationship with the pathophysiological aspects of that condition and their potential clinical applications.

Keywords: Bipolar disorder; Diffusion tensor imaging; Functional neuroimaging; Magnetic resonance imaging.

PubMed Disclaimer

Similar articles

Cited by

References

    1. Abe C, Liberg B, Song J, Bergen SE, Petrovic P, Ekman CJ, Sellgren CM, Ingvar M, Landen M (2019) Longitudinal cortical thickness changes in bipolar disorder and the relationship to genetic risk, mania, and lithium use. Biol Psychiatry 87(3):271–281. https://doi.org/10.1016/j.biopsych.2019.08.015 - DOI - PubMed
    1. Abramovic L, Boks MPM, Vreeker A, Verkooijen S, van Bergen AH, Ophoff RA, Kahn RS, van Haren NEM (2018) White matter disruptions in patients with bipolar disorder. Eur Neuropsychopharmacol 28(6):743–751. https://doi.org/10.1016/j.euroneuro.2018.01.001 - DOI - PubMed - PMC
    1. Adler CM, Holland SK, Schmithorst V, Wilke M, Weiss KL, Pan H, Strakowski SM (2004) Abnormal frontal white matter tracts in bipolar disorder: a diffusion tensor imaging study. Bipolar Disord 6(3):197–203. https://doi.org/10.1111/j.1399-5618.2004.00108.x - DOI - PubMed
    1. Adler CM, Adams J, DelBello MP, Holland SK, Schmithorst V, Levine A, Jarvis K, Strakowski SM (2006) Evidence of white matter pathology in bipolar disorder adolescents experiencing their first episode of mania: a diffusion tensor imaging study. Am J Psychiatry 163(2):322–324. https://doi.org/10.1176/appi.ajp.163.2.322 - DOI - PubMed
    1. Alexander AL, Lee JE, Lazar M, Field AS (2007) Diffusion tensor imaging of the brain. Neurotherapeutics 4(3):316–329. https://doi.org/10.1016/j.nurt.2007.05.011 - DOI - PubMed - PMC