Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Oct;25(5):544-550.
doi: 10.1111/1744-9987.13599. Epub 2020 Oct 27.

Novel coronavirus disease in patients with end-stage kidney disease

Affiliations
Review

Novel coronavirus disease in patients with end-stage kidney disease

Noriaki Shimada et al. Ther Apher Dial. 2021 Oct.

Abstract

The novel coronavirus disease outbreak started in Wuhan, China, in December 2019 and has since spread rapidly worldwide. As almost all patients with end-stage kidney disease have been treated with HD in Japan, they have a higher risk of infection than the healthy population. Moreover, the complications of renal failure, such as hypertension and cardiovascular diseases, appear to be a risk factor of death owing to novel coronavirus disease. The reported morbidity and mortality rates of novel coronavirus disease are significantly higher in dialysis patients than in the healthy population. No treatment for novel coronavirus disease has yet been developed; thus, countermeasures to prevent the spread of coronavirus disease in dialysis facilities must be rapidly established. The latest findings on novel coronavirus disease in patients with end-stage kidney disease and the guidelines for countermeasures against the spread of novel coronavirus disease worldwide are summarized in this review.

Keywords: COVID-19; infection control; kidney failure; renal dialysis.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflicts of interest.

References

    1. World Health Organization . As of 3:12 pm CEST, 3 October 2020, World Health Organization coronavirus disease (COVID‐19) dashboard [cited 2020 Oct 5]. Available from: https://covid19.who.int/
    1. Xu X, Chen P, Wang J, et al. Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission. Sci China Life Sci. 2020;63:457–460. 10.1007/s11427-020-1637-5. - DOI - PMC - PubMed
    1. Zhou P, Yang XL, Wang XG, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature. 2020;579:270–273. 10.1038/s41586-020-2012-7. - DOI - PMC - PubMed
    1. Hoffmann M, Klein‐Weber H, Schroeder S, et al. SARS‐CoV‐2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. Cell. 2020;181:271–280. 10.1016/j.cell.2020.02.052. - DOI - PMC - PubMed
    1. Li MY, Zhang Y, Wang XS. Expression of the SARS‐CoV‐2 cell receptor gene ACE2 in a wide variety of human tissues. Infect Dis Poverty. 2020;9:45. 10.1186/s40249-020-00662-x. - DOI - PMC - PubMed