Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Multicenter Study
. 2021 Apr;42(4):467-470.
doi: 10.1017/ice.2020.462. Epub 2020 Oct 12.

Surgeon choice in the use of postdischarge antibiotics for prophylaxis following mastectomy with and without breast reconstruction

David K Warren  1 , Katelin B Nickel  1 , Christopher J Hostler  2   3 , Katherine Foy  2 , Jennifer H Han  4   5   6 , Pam Tolomeo  5 , Ian R Banks  1 , Victoria J Fraser  1 , Margaret A Olsen  1   7 ; CDC Prevention Epicenter Program
Affiliations
Multicenter Study

Surgeon choice in the use of postdischarge antibiotics for prophylaxis following mastectomy with and without breast reconstruction

David K Warren et al. Infect Control Hosp Epidemiol. 2021 Apr.

Abstract

Multiple guidelines recommend discontinuation of prophylactic antibiotics <24 hours after surgery. In a multicenter, retrospective cohort of 2,954 mastectomy patients ± immediate breast reconstruction, we found that utilization of prophylactic postdischarge antibiotics varied dramatically at the surgeon level among general surgeons and was virtually universal among plastic surgeons.

PubMed Disclaimer

Conflict of interest statement

Conflicts of interest

MAO reports consultant work with Pfizer and grant funding through Pfizer, Merck, and Sanofi Pasteur for work outside the submitted manuscript. VJF reports her spouse is the Chief Clinical Officer at Cigna Corporation. DKW reports consultant work with Centene Corp., PDI Inc., Pursuit Vascular, Homburg & Partner, and Carefusion/BD and is a sub-investigator for a Pfizer-sponsored study for work outside the submitted manuscript. JHH reports that the present work was conducted during her affiliation with the University of Pennsylvania. JHH is currently an employee of, and holds shares in, the GSK group of companies. No other authors report conflicts of interest relevant to this article.

Figures

Figure 1.
Figure 1.. Proportion of individual surgeon’s mastectomy patients prescribed prophylactic post-discharge antibiotics stratified by surgeon volume and specialty (plastic surgeon [A] versus general surgeon [B]).
The dashed line represents the overall proportion of post-discharge antibiotics among procedures overseen by a plastic and general surgeon, respectively. Plastic and general surgeon annual volume thresholds were based on the distribution of annual volume within the surgeon specialty and are displayed in the x axes of the plots..
Figure 1.
Figure 1.. Proportion of individual surgeon’s mastectomy patients prescribed prophylactic post-discharge antibiotics stratified by surgeon volume and specialty (plastic surgeon [A] versus general surgeon [B]).
The dashed line represents the overall proportion of post-discharge antibiotics among procedures overseen by a plastic and general surgeon, respectively. Plastic and general surgeon annual volume thresholds were based on the distribution of annual volume within the surgeon specialty and are displayed in the x axes of the plots..
See this image and copyright information in PMC

References

    1. Berrios-Torres SI, Umscheid CA, Bratzler DW, et al. Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017. JAMA Surg 2017;152:784–791. - PubMed
    1. Alderman A, Gutowski K, Ahuja A, Gray D. ASPS Clinical Practice Guideline Summary on Breast Reconstruction with Expanders and Implants. Plast. Reconstr. Surg 2014;134:648e–655e. - PubMed
    1. Phillips BT, Wang ED, Mirrer J, et al. Current Practice among Plastic Surgeons of Antibiotic Prophylaxis and Closed-Suction Drains in Breast Reconstruction: Experience, Evidence, and Implications for Postoperative Care. Ann. Plast. Surg 2011;66:460–465. - PubMed
    1. Brahmbhatt RD, Huebner M, Scow JS, et al. National Practice Patterns in Preoperative and Postoperative Antibiotic Prophylaxis in Breast Procedures Requiring Drains: Survey of the American Society of Breast Surgeons. Ann. Surg. Oncol 2012;19:3205–3211. - PMC - PubMed
    1. Elixhauser A, Steiner C, Harris R, Coffey RM. Comorbidity Measures for Use with Administrative Data. Med. Care 1998;36:8–27. - PubMed

Publication types

Substances