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Comparative Study
. 1977 Aug;17(2):463-5.
doi: 10.1128/iai.17.2.463-465.1977.

Blastogenic transformation by lipopolysaccharide of blood leukocytes from immunized but not normal cattle

G G Schurig, J R Duncan, J Case, A J Winter
Comparative Study

Blastogenic transformation by lipopolysaccharide of blood leukocytes from immunized but not normal cattle

G G Schurig et al. Infect Immun. 1977 Aug.

Abstract

Escherichia coli lipopolysaccharide produced blastogenic transformation in whole-blood leukocytes from heifers that had been infected and immunized with Campylobacter fetus, but not in cells from control animals. This suggests that lipopolysaccharide dose not function as a B-cell mitogen in cattle and that its stimulation of cells from immunized animals occurred through another mechanism.

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