Trajectories of functional ability over the life course: a conceptual model of the interaction of stressor-induced functional loss and resilience
- PMID: 33041497
- PMCID: PMC7544242
- DOI: 10.1002/sdr.1611
Trajectories of functional ability over the life course: a conceptual model of the interaction of stressor-induced functional loss and resilience
Abstract
Understanding the factors that influence functional ability over the life course is integral to identifying clinical and public health policies to facilitate successful aging. The World Health Organization has advocated a conceptual framework to clarify the policy discussion. We have sought to translate this general framework into an explicit system dynamics model of the interaction of physiological loss, stressors and endogenous responses to produce a familiar variety of trajectories of functional ability over the life courses. Simulation experiments were implemented for both a 30-month duration with only one major stressor; and for the life course with an initial major stressor and subsequent stressors determined by the level of functional ability. For both contexts, variations in the few parameters in the scenarios led to a realistic range of trajectories of function over time.
Conflict of interest statement
Conflict of interest The authors declare that they have no competing interests.
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References
-
- Baker GT, Martin GR. 1997. Molecular and biologic factors in aging: the origins, causes, and prevention of senescence In Geriatric medicine, Cassel CK, Cohen HJ, Larson EB, Meier DE, Resnick NM, Rubenstein LZ, Sorensen LB (eds). Springer: New York.
-
- Beard J, Officer A, de Carvalho IA, Sadana R, Pot AM, Michel JP, Lloyd-Sherlock P, Epping-Jordan JE, Peeters GMEEG, Mahanani WR, Thiyagarajan JA, Chatterji S. 2015. World report on aging and health. World Health Organization: Geneva.
-
- Bielak AAM, Anstey KJ, Christensen H, Windor TD. 2012. Activity engagement is related to level, but not change in cognitive ability across adulthood. Psychology and Aging 27: 219–228. - PubMed
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