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Case Reports
. 2020 Sep 6;12(9):e10272.
doi: 10.7759/cureus.10272.

Not All Fun and Games: A Case Report of Contact Dermatitis Related to Slime and Play-Doh

Brett C Brazen  1 , Brooke Wehausen  2 , Andleeb A Usmani  2   3
Affiliations
Case Reports

Not All Fun and Games: A Case Report of Contact Dermatitis Related to Slime and Play-Doh

Brett C Brazen et al. Cureus. .

Abstract

Slime and Play-Doh have been gaining popularity among adolescents and preteens. Both are gooey, viscoelastic substances that can be morphed and molded into virtually anything imaginable. Slime can be made from several household products including school glue and borax, which have both been linked to cases of irritant and allergic contact dermatitis, conditions that historically involve activation of many immune-regulatory cells such as Langerhans' cells and T cells. We review the rising incidence of contact dermatitis related to Slime and Play-Doh, pathogenesis, and hallmark findings, along with several treatment options to help clinicians expediently diagnose and treat the condition.

Keywords: allergic dermatoses; contact dermatitis; dermatology; genodermatoses; irritant contact dermatitis; medical dermatology.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Hyperpigmented macules on the dorsum of the left hand and second to fourth interphalangeal joints of the right hand (superior view)
Figure 2
Figure 2. Hyperpigmented macules on the dorsum of the left hand and second to fourth interphalangeal joints of the right hand (superolateral view)
Figure 3
Figure 3. Hyperpigmented salmon-colored macules on the superior aspect of the knees bilaterally
See this image and copyright information in PMC

References

    1. Allergic contact dermatitis: epidemiology, molecular mechanisms, in vitro methods and regulatory aspects. Peiser M, Tralau T, Heidler J, et al. Cell Mol Life Sci. 2012;69:763–781. - PMC - PubMed
    1. α-Amylase, a flour additive: an important cause of protein contact dermatitis in bakers. Morren MA, Janssens V, Dooms-Goossens A, Van Hoeyveld E, Cornelis A, De Wolf-Peeters C, Heremans A. J Am Acad Dermatol. 1993;29:723–728. - PubMed
    1. Dermatology for the allergist. Kim D, Lockey R. World Allergy Organ J. 2010;3:202–215. - PMC - PubMed
    1. Contact dermatitis: allergic and irritant. Tan C-H, Rasool S, Johnston GA. Clin Dermatol. 2014;32:116–124. - PubMed
    1. Exposure to flour dust in the occupational environment. Stobnicka A, Górny RL. Int J Occup Saf Ergon. 2015;21:241–249. - PMC - PubMed

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