Partial structure of an insulin-sensitive glycophospholipid
- PMID: 3304285
- DOI: 10.1016/0006-291x(87)90595-x
Partial structure of an insulin-sensitive glycophospholipid
Abstract
The structure of a glycophospholipid, which has been involved in insulin action, has been investigated using H35 cells and rat liver membranes. The present evidence indicates that this molecule contains a phosphatidyl-chiro-inositol moiety, glycosidically linked to a non-N-acetylated glucosamine. In addition, the polar head group of the lipid contains galactose, probably four residues, and a total number of three phosphates.
Similar articles
-
Identification of a novel insulin-sensitive glycophospholipid from H35 hepatoma cells.J Biol Chem. 1987 Feb 15;262(5):2131-7. J Biol Chem. 1987. PMID: 3546286
-
Inhibition of cyclic AMP-dependent protein kinase by the polar head group of an insulin-sensitive glycophospholipid.Biochim Biophys Acta. 1988 Jan 18;968(1):69-76. doi: 10.1016/0167-4889(88)90045-6. Biochim Biophys Acta. 1988. PMID: 3337845
-
The polar head group of a novel insulin-sensitive glycophospholipid mimics insulin action on phospholipid methyltransferase.FEBS Lett. 1986 Dec 15;209(2):238-42. doi: 10.1016/0014-5793(86)81119-x. FEBS Lett. 1986. PMID: 3539637
-
In search of a second messenger for insulin.Am J Physiol. 1988 Jul;255(1 Pt 1):C1-11. doi: 10.1152/ajpcell.1988.255.1.C1. Am J Physiol. 1988. PMID: 2839033 Review.
-
[Hormone receptor and stimulated turnover of inositol phospholipids; role of PI response in the enhancement of Ca2+ influx].Tanpakushitsu Kakusan Koso. 1982 Aug;27(10):1291-305. Tanpakushitsu Kakusan Koso. 1982. PMID: 6294743 Review. Japanese. No abstract available.
Cited by
-
A phosphatidylinositol-linkage-deficient T-cell mutant contains insulin-sensitive glycosyl-phosphatidylinositol.Biochem J. 1992 Mar 15;282 ( Pt 3)(Pt 3):681-6. doi: 10.1042/bj2820681. Biochem J. 1992. PMID: 1532490 Free PMC article.
-
Transport in isolated rat hepatocytes of the phospho-oligosaccharide that mimics insulin action. Effects of adrenalectomy and glucocorticoid treatment.Biochem J. 1991 Mar 1;274 ( Pt 2)(Pt 2):369-74. doi: 10.1042/bj2740369. Biochem J. 1991. PMID: 2006906 Free PMC article.
-
Isolation of insulin-sensitive phosphatidylinositol-glycan from rat adipocytes. Its impaired breakdown in the streptozotocin-diabetic rat.Biochem J. 1990 Oct 15;271(2):427-35. doi: 10.1042/bj2710427. Biochem J. 1990. PMID: 2173562 Free PMC article.
-
The effect of amino acids, monoamines and polyamines on pyruvate dehydrogenase activity in mitochondria from rat adipocytes.Mol Cell Biochem. 1990 Mar 27;93(2):195-206. doi: 10.1007/BF00226192. Mol Cell Biochem. 1990. PMID: 2345544
-
The role of glycosyl-phosphoinositides in hormone action.J Bioenerg Biomembr. 1991 Feb;23(1):29-41. doi: 10.1007/BF00768837. J Bioenerg Biomembr. 1991. PMID: 1849135 Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical