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. 1987 Jul 31;146(2):870-7.
doi: 10.1016/0006-291x(87)90611-5.

Computer-assisted predictions of signal peptidase processing sites

R J Folz, J I Gordon

Computer-assisted predictions of signal peptidase processing sites

R J Folz et al. Biochem Biophys Res Commun. .

Abstract

Computer programs are presented which incorporate 2 different algorithms for predicting the site of signal peptide cleavage for eukaryotic preproteins. These programs can be used to identify sites of signal peptidase cleavage of putative preproteins to facilitate the design and interpretation of signal peptide mutagenesis experiments, and to engineer artificial prepolypeptides.

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