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Review
. 2020 Sep 15:8:567184.
doi: 10.3389/fpubh.2020.567184. eCollection 2020.

Seasonality of Respiratory Viral Infections: Will COVID-19 Follow Suit?

Amani Audi  1   2 , Malak AlIbrahim  1   2 , Malak Kaddoura  1   2 , Ghina Hijazi  1   2 , Hadi M Yassine  3 , Hassan Zaraket  1   2
Affiliations
Review

Seasonality of Respiratory Viral Infections: Will COVID-19 Follow Suit?

Amani Audi et al. Front Public Health. .

Abstract

Respiratory viruses, including coronaviruses, are known to have a high incidence of infection during winter, especially in temperate regions. Dry and cold conditions during winter are the major drivers for increased respiratory tract infections as they increase virus stability and transmission and weaken the host immune system. The novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged in China in December 2020 and swiftly spread across the globe causing substantial health and economic burdens. Several countries are battling with the second wave of the virus after a devastating first wave of spread, while some are still in the midst of their first wave. It remains unclear whether SARS-CoV-2 will eventually become seasonal or will continue to circulate year-round. In an attempt to address this question, we review the current knowledge regarding the seasonality of respiratory viruses including coronaviruses and the viral and host factors that govern their seasonal pattern. Moreover, we discuss the properties of SARS-CoV-2 and the potential impact of meteorological factors on its spread.

Keywords: COVID-19; coronaviruses; humidity; respiratory viruses; seasonality; severe acute respiratory syndrome coronavirus-2; temperature.

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References

    1. Zhou P, Yang X, Wang X-G, Hu B, Zhang L, Zhang W, et al. . A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature. (2020) 579:270–3. 10.1038/s41586-020-2012-7 - DOI - PMC - PubMed
    1. World Health Organization Coronavirus Disease (COVID-19) Situation Reports. (2020) Available online at: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/situatio... (accessed May 13, 2020).
    1. Perlman S, McIntosh K. Coronaviruses, including severe acute respiratory syndrome (SARS) and middle east respiratory syndrome (MERS). In: Bennett JE, Dolin R, Blaser MJ. editors. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. Philadelphia, PA: Elsevier; (2015) p. 2073–80.
    1. Docea AO, Tsatsakis A, Albulescu D, Cristea O, Zlatian O, Vinceti M, et al. . A new threat from an old enemy: re-emergence of coronavirus (review). Int J Mol Med. (2020) 45:1631–43. 10.3892/ijmm.2020.4555 - DOI - PMC - PubMed
    1. Fehr AR, Perlman S. Coronaviruses: an overview of their replication and pathogenesis. Methods Mol Biol. (2015) 1282:1–23. 10.1007/978-1-4939-2438-7_1 - DOI - PMC - PubMed