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. 2020 Jun 15;7(4):366-371.
doi: 10.14744/nci.2020.57767. eCollection 2020.

Salivary gland tumors: A 15-year experience of a university hospital in Turkey

Erdem Mengi  1 , Cuneyt Orhan Kara  1 , Funda Tumkaya  1 , Fazil Necdet Ardic  1 , Bulent Topuz  1 , Ferda Bir  2
Affiliations

Salivary gland tumors: A 15-year experience of a university hospital in Turkey

Erdem Mengi et al. North Clin Istanb. .

Abstract

Objective: To determine the demographic characteristics of benign and malignant salivary gland tumors in our department in the last 15 years.

Methods: In this study, the files of the patients who underwent salivary gland surgery between 2004 and 2019 in our department were analyzed retrospectively. A total of 366 patients whose diagnoses of salivary gland tumor histopathologically confirmed were included in this study. The demographic data of the patients and tumor localizations were recorded, and their relationships with histopathological results were examined.

Results: Of the 366 tumors, 292 (80%) of them was originated from the parotid gland, 52 (14%) from the submandibular gland, and 22 (6%) from the minor salivary gland. The male: female ratio was found as 1.2:1, and the mean age of the patients was 50.37 years. A total of 259 (70.8%) tumors were benign, and 107 (29.2%) were malignant. The most frequent benign tumor was pleomorphic adenoma, with 121 cases (46.7%). While pleomorphic adenomas constituted the majority of the benign tumors of the submandibular gland and minor salivary glands, Warthin tumor was detected more than pleomorphic adenoma in the parotid gland. The most common malignant tumor was mucoepidermoid carcinoma, with 26 cases (24.3%).

Conclusion: The distribution of the salivary gland tumors detected in our department was found to be substantially similar to other worldwide series. Unlike the literature, we concluded that salivary gland tumors were seen slightly more in males, minor salivary gland tumors were relatively rare and Warthin tumors were more frequently detected in our region.

Keywords: Histology; minor salivary gland; parotid; salivary gland tumor; submandibular.

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Conflict of interest statement

Conflict of Interest: No conflict of interest was declared by the authors.

Figures

FIGURE 1
FIGURE 1
The site of origin of the salivary gland tumors.
FIGURE 2
FIGURE 2
Distribution of the salivary gland tumors according to age group.
FIGURE 3
FIGURE 3
Malignancy rates for salivary gland tumors according to the site of origin.
FIGURE 4
FIGURE 4
Distribution of pleomorphic adenomas and Warthin tumors according to age group. While pleomorphic adenoma has a much wider range of age, Warthin tumor is seen to peak between the ages of 51 and 60.
See this image and copyright information in PMC

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