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Review
. 2021 Jan;43(1):345-353.
doi: 10.1002/hed.26486. Epub 2020 Oct 12.

Transoral endoscopic thyroidectomy vestibular approach vs conventional open thyroidectomy: Meta-analysis

Yichao Wang  1 , Shengliang Zhou  2 , Xueting Liu  3 , Shu Rui  1 , Zhihui Li  1 , Jingqiang Zhu  1 , Tao Wei  1
Affiliations
Review

Transoral endoscopic thyroidectomy vestibular approach vs conventional open thyroidectomy: Meta-analysis

Yichao Wang et al. Head Neck. 2021 Jan.

Abstract

Background: To conduct a meta-analysis to compare the safety and efficacy of transoral endoscopic thyroidectomy vestibular approach (TOETVA) with conventional open thyroidectomy (COT).

Methods: MEDLINE, EMBASE, Science Citation Index Expanded, and the Cochrane Central Register of Controlled Trials in the Cochrane Library from January 2007 to March 2020 were searched to identify studies comparing TOETVA and COT.

Results: Six eligible nonrandomized studies involving 1151 patients were included. Meta-analysis results revealed that TOETVA group had a significantly longer operative time (weighted mean difference [WMD], 66.09; 95% confidence interval [CI], 35.22-96.96; P < .0001) and larger amount of drainage (WMD, 98; 95% CI, 20.14-175.86; P = .01). There were no significant differences in terms of postoperative outcomes.

Conclusion: TOETVA appears to be as feasible and safe as the COT for the treatment of patients with benign thyroid nodules and selected differential thyroid carcinomas.

Keywords: COT; TOETVA; meta-analysis; minimally invasive surgery.

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References

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