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Case Reports
. 2021 Feb;26(2):e336-e337.
doi: 10.1002/onco.13563. Epub 2020 Oct 23.

To Transplant or Not to Transplant During the SARS-CoV-2 Pandemic? That Is the Question

Affiliations
Case Reports

To Transplant or Not to Transplant During the SARS-CoV-2 Pandemic? That Is the Question

Dario Marino et al. Oncologist. 2021 Feb.

Abstract

The novel coronavirus disease 2019 has grown to be a global public health emergency. The rapid spread of the infection has raised many questions in the oncohematological scientific community regarding the appropriateness of high-dose chemotherapy with autologous stem cell transplantation (ASCT). We here report two cases of patients who received ASCT at our Institute during the epidemic in Italy, affected with Hodgkin lymphoma and germ cell tumor, respectively. The two patients underwent a nasopharyngeal swab for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on hospital admittance and during the period of bone marrow aplasia. They were attended to exclusively by dedicated health care staff who followed specifically implemented protocols for bedside nursing and care. They completed the procedure without unexpected side effect. Our experience demonstrates how ASCT can be performed safely if procedures are reorganized ad hoc to reduce the risk of SARS-CoV-2 infection.

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Conflict of interest statement

Disclosures of potential conflicts of interest may be found at the end of this article.

References

    1. Mahmoudjafari Z, Alexander M, Roddy J et al. American Society for Transplantation and Cellular Therapy Pharmacy Special Interest Group position statement on pharmacy practice management and clinical management for COVID‐19 in hematopoietic cell transplantation and cellular therapy patients in the United States. Biol Blood Marrow Transplant 2020;26:1043–1049. - PMC - PubMed
    1. Dholaria B, Savani BN. How do we plan hematopoietic cell transplant and cellular therapy with the looming COVID‐19 threat? Br J Haematol 2020;189:239–240. - PMC - PubMed
    1. Coronavirus Disease COVID‐19: EBMT Recommendations Update April 7, 2020. Barcelona, Spain: European Society for Blood and Marrow Transplantation, 2020. Available at https://www.ebmt.org/sites/default/files/2020-04/EBMT-COVID-19-guideline.... Accessed April 7, 2020.
    1. Barrington SF, Kirkwood AA, Franceschetto A et al. PET‐CT for staging and early response: Results from the Response‐Adapted Therapy in Advanced Hodgkin Lymphoma study. Blood 2016;127:1531–1538. - PubMed
    1. International Germ Cell Cancer Collaborative Group . International Germ Cell Consensus Classification: A prognostic factor‐based staging system for metastatic germ cell cancers. J Clin Oncol 1997;15:594–603. - PubMed

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