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Observational Study
. 2020 Oct 13;20(1):333.
doi: 10.1186/s12876-020-01463-0.

Validation of the Moroccan arabic version of the low anterior resection syndrome score

Hajar Essangri  1 , Mohammed Anass Majbar  1 , Amine Benkabbou  1 , Laila Amrani  1 , Raouf Mohsine  1 , Amine Souadka  2
Affiliations
Observational Study

Validation of the Moroccan arabic version of the low anterior resection syndrome score

Hajar Essangri et al. BMC Gastroenterol. .

Abstract

Background: Sphincter sparing surgery is oftentimes associated with bowel dysfunction complaints, namely the low anterior resection syndrome (LARS). The LARS questionnaire is widely used to assess this syndrome. The aim of this observational study is to translate this tool into arabic and test its psychometric properties in rectal cancer patients, in order to ease its use in clinical practice and future research.

Methods: The LARS questionnaire was translated to arabic and administered to a total of 143 patients. A subgroup of 42 patients took the test twice for test-retest reliability. Internal consistency was examined through cronbach's alpha. The score results were correlated to the EORTC QLQ-C30 questionnaire for convergent validity assessment, while discriminant validity was established through the ability of the LARS score to differentiate patients with different clinical and pathological criteria.

Results: The Moroccan Arabic version of the LARS score was completed by 143 patients. The internal consistency was demonstrated through a cronbach alpha score of 0.66. The agreement between the test and retest was established by a Bland Altman plot with 95% limits of agreement. 85.6% of patients remained in the same LARS category. The LARS score showed negative correlation with all five of the QLQ-C30 functional scales as well as positive correlation to the diarrhea symptom scale. The questionnaire score differed between patients according to their tumor location, chemoradiotherapy, type of mesorectal excision and anastomosis.

Conclusion: The Moroccan Arabic version of the LARS score shows good psychometric properties and can be used for bowel dysfunction assessment in clinical and research settings.

Keywords: Low anterior resection syndrome; Patient outcome assessment; Postoperative complications; Psychometrics; Quality of life; Rectal neoplasms.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1
Fig. 1
Patient selection flowchart
Fig. 2
Fig. 2
Bland–Altman plot with 95% limits of agreement illustrating the difference between LARS scores at the first and second test
Fig. 3
Fig. 3
Boxplots illustrating the LARS total score according to: (a) rectal tumor location, (b) anastomosis type, (c) radiochemotherapy administration or not, (d) type of mesorectal excision
See this image and copyright information in PMC

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