Blowing Away Fatty Liver: Mission Impossible?

Anna E B McLean¹, Frédéric Gagnadoux^{2

3}, Brendon J Yee^{1

4}

Affiliations

¹ Department of Respiratory and Sleep Medicine Royal Prince Alfred Hospital Sydney, New South Wales, Australia.
² Department of Respiratory and Sleep Medicine University Hospital of Angers Angers, France.
³ INSERM UMR 1063 University of Angers Angers, France and.
⁴ Sydney Medical School The University of Sydney Sydney, New South Wales, Australia.

Editorial

Anna E B McLean et al. Am J Respir Crit Care Med. 2021.

. 2021 Feb 15;203(4):412-413.

doi: 10.1164/rccm.202009-3578ED.

Anna E B McLean¹, Frédéric Gagnadoux^{2

3}, Brendon J Yee^{1

4}

¹ Department of Respiratory and Sleep Medicine Royal Prince Alfred Hospital Sydney, New South Wales, Australia.
² Department of Respiratory and Sleep Medicine University Hospital of Angers Angers, France.
³ INSERM UMR 1063 University of Angers Angers, France and.
⁴ Sydney Medical School The University of Sydney Sydney, New South Wales, Australia.

No abstract available

Comment on

Continuous Positive Airway Pressure Does Not Improve Nonalcoholic Fatty Liver Disease in Patients with Obstructive Sleep Apnea. A Randomized Clinical Trial.
Ng SSS, Wong VWS, Wong GLH, Chu WCW, Chan TO, To KW, Ko FWS, Chan KP, Hui DS. Ng SSS, et al. Am J Respir Crit Care Med. 2021 Feb 15;203(4):493-501. doi: 10.1164/rccm.202005-1868OC. Am J Respir Crit Care Med. 2021. PMID: 32926803 Clinical Trial.

1. Younossi ZM, Koenig AB, Abdelatif D, Fazel Y, Henry L, Wymer M. Global epidemiology of nonalcoholic fatty liver disease-meta-analytic assessment of prevalence, incidence, and outcomes. Hepatology. 2016;64:73–84. - PubMed
1. Tanné F, Gagnadoux F, Chazouillères O, Fleury B, Wendum D, Lasnier E, et al. Chronic liver injury during obstructive sleep apnea. Hepatology. 2005;41:1290–1296. - PubMed
1. Trzepizur W, Boursier J, Le Vaillant M, Ducluzeau PH, Dubois S, Henni S, et al. on the behalf of the METABOL group. Increased liver stiffness in patients with severe sleep apnoea and metabolic comorbidities. Eur Respir J. 2018;51:1800601. - PubMed
1. Mesarwi OA, Loomba R, Malhotra A. Obstructive sleep apnea, hypoxia, and nonalcoholic fatty liver disease. Am J Respir Crit Care Med. 2019;199:830–841. - PMC - PubMed
1. Gaines J, Vgontzas AN, Fernandez-Mendoza J, Bixler EO. Obstructive sleep apnea and the metabolic syndrome: the road to clinically-meaningful phenotyping, improved prognosis, and personalized treatment. Sleep Med Rev. 2018;42:211–219. - PMC - PubMed