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Review
. 2020 Jul;36(4):404-408.
doi: 10.1007/s12055-019-00875-2. Epub 2020 Mar 4.

Thymoma associated with pure red cell aplasia: a case report and literature review

Reenus Demel Xavier  1 , Sujith Devaraj  1 , Vijay Sadasivam  1 , Om Prakasam  1 , Narendra Menon  1 , Ashok Hariharan  1 , Thiagarajamurthy Sundaramoorthi  1
Affiliations
Review

Thymoma associated with pure red cell aplasia: a case report and literature review

Reenus Demel Xavier et al. Indian J Thorac Cardiovasc Surg. 2020 Jul.

Abstract

Pure red cell aplasia (PRCA) is a rare hematological complication associated with thymoma. Remission of PRCA occurs after thymectomy but can reappear after a latency period even without recurrence of thymoma. We report a case and we have reviewed the literature of thymoma associated with PRCA. Because of less number of reported cases, there have been no clinical trials investigating the immunosuppression regimen following thymectomy for thymoma associated with PRCA. After reviewing the literature, we came to a conclusion that thymectomy followed by immumosuppression with the cyclosporin-containing regimen is currently the most effective treatment.

Keywords: Pure red cell aplasia (PRCA); Thymectomy; Thymoma.

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Conflict of interest statement

Conflict of interestThe authors declare that they have no conflicts of interest.

Figures

Fig. 1
Fig. 1
Computed tomography of chest showing a well-defined mass in the anterior mediastinum
Fig. 2
Fig. 2
Microscopic appearance of thymoma that shows spindle-shaped cells and lobules of thymocytes with lymphocytes (hematoxylin and eosin; × 100)
See this image and copyright information in PMC

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