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Case Reports
. 2020 Sep 22:13:2329-2332.
doi: 10.2147/JPR.S271535. eCollection 2020.

A Rare Case of Euphoria Caused by Lidocaine After an Erector Spinae Plane Block: A Case Report

Affiliations
Case Reports

A Rare Case of Euphoria Caused by Lidocaine After an Erector Spinae Plane Block: A Case Report

Joo Yong Lee et al. J Pain Res. .

Abstract

Lidocaine is a cost-effective drug that is widely used for local and regional anesthesia. However, central nervous system (CNS) toxicity can occur when lidocaine is administered above the maximum recommended dose (approximately 4.5 mg/kg) or if lidocaine is injected intravascularly rather than administered locally. Systemic toxicity by lidocaine has been reported in several studies. However, psychotic reactions due to lidocaine have been rarely reported; furthermore, reports of lidocaine-related euphoria are very rare. We report a very rare case of euphoria caused by CNS toxicity that occurred during the local administration of lidocaine at the therapeutic dose. Therefore, anesthesiologists should be aware of the severe side effects of local anesthetics despite administering the appropriate dosage at the appropriate location. Future studies should investigate pharmacokinetics to determine the safety profile of local anesthetics.

Keywords: adverse effects; euphoria; lidocaine; nerve block.

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Conflict of interest statement

The authors declare that they have no competing interests for this work.

References

    1. McCaughey W. Adverse effects of local anaesthetics. Drug Saf. 1992;7(3):178–189. doi: 10.2165/00002018-199207030-00003 - DOI - PubMed
    1. Scott DB. Toxic effects of local anaesthetic agents on the central nervous system. Br J Anaesth. 1986;58(7):732–735. doi: 10.1093/bja/58.7.732 - DOI - PubMed
    1. Park HS, Chung CJ, Chin YJ. The plasma concentrations and systemic toxicity of lidocaine after maximal or supramaximal recommended doses of epidural administration. Korean J Pain. 1999;12:36–42.
    1. Song SO, Suh YH. Changes of plasma lidocaine concentrations after Stellate Ganglion Block according to volume-changes of 1% lidocaine. Korean J Pain. 2001;14:26–31.
    1. Weinberg L, Peake B, Tan C, Nikfarjam M. Pharmacokinetics and pharmacodynamics of lignocaine: a review. World J Anesthesiol. 2015;4(2):17–29. doi: 10.5313/wja.v4.i2.17 - DOI

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