Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2020 Jun 15;7(6):e00411.
doi: 10.14309/crj.0000000000000411. eCollection 2020 Jun.

Breast Cancer Metastasis Presenting as Colonic Polyps

Affiliations
Case Reports

Breast Cancer Metastasis Presenting as Colonic Polyps

Jamie Bering et al. ACG Case Rep J. .

Abstract

Breast cancer is the most common malignancy among women and is the second leading cause of cancer-related death among women in the United States. Rarely, breast cancer can metastasize to the gastrointestinal tract. We present a case of metastatic breast cancer diagnosed after finding metastatic lesions appearing as polyps during a colonoscopy.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Colonoscopy showing (A) a 2-mm cecal polyp and (B) a 2-mm transverse colon polyp.
Figure 2.
Figure 2.
Immunohistochemical staining of the tumor showing (A) atypical tumor cells with signet ring features and invasion of the lamina propria (hematoxylin and eosin stain, 20× magnification), (B) atypical tumor cells with signet ring features (hematoxylin and eosin stain, 40× magnification), and (C) strong diffuse positive GATA3 representing metastasis from primary breast carcinoma.

References

    1. DeSantis CE, Ma J, Gaudet MM, et al. Breast cancer statistics, 2019. CA Cancer J Clin. 2019;69(6):438–51. - PubMed
    1. Takeuchi H, Hiroshige S, Yoshikawa Y, Kusumoto T, Muto Y. A case of synchronous metastasis of breast cancer to stomach and colon. Anticancer Res. 2012;32(9):4051–5. - PubMed
    1. Uygun K, Kocak Z, Altaner S, Cicin I, Tokatli F, Uzal C. Colonic metastasis from carcinoma of the breast that mimics a primary intestinal cancer. Yonsei Med J. 2006;47(4):578–82. - PMC - PubMed
    1. Nejati P, Sadeghi M, Amirian F, Ramezani M. Metastatic breast cancer to colon: An unusual site of metastasis with a review of literature. Biomed Res Ther. 2019;6(3):3088–92.
    1. Sobinsky JD, Willson TD, Podbielski FJ, Connolly MM. Unusual metastatic patterns of invasive lobular carcinoma of the breast. Case Rep Oncol Med. 2013;2013:986517. - PMC - PubMed

Publication types