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Comment
. 2020 Oct 15;183(2):305-307.
doi: 10.1016/j.cell.2020.09.046.

Colonic Macrophages Combat Fungal Intoxication: Metchnikoff Would Be Pleased

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Colonic Macrophages Combat Fungal Intoxication: Metchnikoff Would Be Pleased

Gwendalyn J Randolph. Cell. .
Free article

Abstract

How the colon microenvironment confronts a breach of its epithelial border remains incompletely understood. In this issue, the laboratories of Lennon-Duménil and Vignjevic reveal a novel role for macrophages in sustaining epithelial integrity in the face of fungal metabolites.

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  • Macrophages Maintain Epithelium Integrity by Limiting Fungal Product Absorption.
    Chikina AS, Nadalin F, Maurin M, San-Roman M, Thomas-Bonafos T, Li XV, Lameiras S, Baulande S, Henri S, Malissen B, Lacerda Mariano L, Barbazan J, Blander JM, Iliev ID, Matic Vignjevic D, Lennon-Duménil AM. Chikina AS, et al. Cell. 2020 Oct 15;183(2):411-428.e16. doi: 10.1016/j.cell.2020.08.048. Epub 2020 Sep 23. Cell. 2020. PMID: 32970988 Free PMC article.

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