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. 2021 Feb 5:246:119004.
doi: 10.1016/j.saa.2020.119004. Epub 2020 Oct 6.

A ratiometric fluorescent sensor based on g-CNQDs@Zn-MOF for the sensitive detection of riboflavin via FRET

Shasha Feng  1 , Fubin Pei  1 , Yi Wu  1 , Jingjing Lv  1 , Qingli Hao  1 , Tinghai Yang  2 , Zhaoyang Tong  3 , Wu Lei  4
Affiliations

A ratiometric fluorescent sensor based on g-CNQDs@Zn-MOF for the sensitive detection of riboflavin via FRET

Shasha Feng et al. Spectrochim Acta A Mol Biomol Spectrosc. .

Abstract

A novel ratiometric fluorescent sensor based on Förster resonance energy transfer (FRET) platform was designed for riboflavin (RF) detection. The graphitic carbon nitrides quantum dots - Zn-MOF composite (g-CNQDs@Zn-MOF) was used as the fluorescent probe. In the FRET system, g-CNQDs@Zn-MOF and RF acted as donor and acceptor, respectively. The probe exhibited high sensitivity and good selectivity to RF, and had been successfully used for the detection of RF in milk and vitamin B2 tablets. The detection limit of the sensor was 15 nM. The strategy expanded the application of MOF in sensing filed and provided a new method for the detection of RF.

Keywords: Fluorescence detection; Ratiometric; Riboflavin; g-CNQDs@Zn-MOF.

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Conflict of interest statement

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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