A Cross-Sectional Study Examining the Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus 2 Antibodies in a University Student Population
- PMID: 33071164
- PMCID: PMC7557277
- DOI: 10.1016/j.jadohealth.2020.09.001
A Cross-Sectional Study Examining the Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus 2 Antibodies in a University Student Population
Abstract
Purpose: The aim of the study was to determine the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in a university student population.
Methods: This was a cross-sectional survey study based on the World Health Organization population-based seroepidemiological investigational protocol for SARS-CoV-2 conducted between April 29, 2020, and May 8, 2020, examining SARS-CoV-2 antibody prevalence among 790 university students in Los Angeles, CA. Participants completed a questionnaire on potential risk factors before blood sampling. Samples were analyzed using the EUROIMMUN Anti-SARS-CoV-2 ELISA (IgG) for the qualitative detection of IgG class antibodies to SARS-CoV-2 in human serum or plasma.
Results: The estimated prevalence of SARS-CoV-2 antibody was 4.0% (3.0%, 5.1%). Factors associated with having a positive test included history of anosmia and/or loss of taste (95% CI: 1.4-9.6). A history of respiratory symptoms, with or without fever, was not associated with a positive antibody test.
Conclusions: Prevalence of SARS-CoV-2 antibodies in the undergraduate and graduate student university population was similar to community prevalence.
Keywords: SARS-CoV-2; Seroprevalence; University.
Copyright © 2020 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.
References
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- National Center for Education Statistics Digest of education statistics. https://nces.ed.gov/programs/digest/d18/tables/dt18_105.30.asptics Available at:
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- United States Census Bureau US and world population clock. https://www.census.gov/popclock/ Available at:
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