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Review
. 2020 May;21(4):240-252.
doi: 10.2174/1389202921999200601144137.

Extremophile Microbial Communities and Enzymes for Bioenergetic Application Based on Multi-Omics Tools

Gislaine Fongaro  1 , Guilherme Augusto Maia  1 , Paula Rogovski  1 , Rafael Dorighello Cadamuro  1 , Joana Camila Lopes  1 , Renato Simões Moreira  1 , Aline Frumi Camargo  1 , Thamarys Scapini  1 , Fábio Spitza Stefanski  1 , Charline Bonatto  1 , Doris Sobral Marques Souza  1 , Patrícia Hermes Stoco  1 , Rubens Tadeu Delgado Duarte  1 , Ariadne Cristiane Cabral da Cruz  1 , Glauber Wagner  1 , Helen Treichel  1
Affiliations
Review

Extremophile Microbial Communities and Enzymes for Bioenergetic Application Based on Multi-Omics Tools

Gislaine Fongaro et al. Curr Genomics. 2020 May.

Abstract

Genomic and proteomic advances in extremophile microorganism studies are increasingly demonstrating their ability to produce a variety of enzymes capable of converting biomass into bioenergy. Such microorganisms are found in environments with nutritional restrictions, anaerobic environments, high salinity, varying pH conditions and extreme natural environments such as hydrothermal vents, soda lakes, and Antarctic sediments. As extremophile microorganisms and their enzymes are found in widely disparate locations, they generate new possibilities and opportunities to explore biotechnological prospecting, including biofuels (biogas, hydrogen and ethanol) with an aim toward using multi-omics tools that shed light on biotechnological breakthroughs.

Keywords: Biodiversity; enzymes; extremophiles; microorganisms; molecular methods; multi-omics.

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Figures

Fig. (1)
Fig. (1)
“Multi-omics” strategies and basic workflows. Based on metagenomic, meta-transcriptomic and metaproteomic approaches to prospect genes and proteins for biotechnological application. (A higher resolution / colour version of this figure is available in the electronic copy of the article).
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References

    1. Rothschild L.J., Mancinelli R.L. Life in extreme environments. Nature. 2001;409(6823):1092–1101. doi: 10.1038/35059215. - DOI - PubMed
    1. Durvasula R., Rao D.V.S. In: Extremophiles: From Biology to Biotechnology; Durvasula, R.V. Rao D.V.S., editor. CRC Press; 2018. pp. 1–18.
    1. Duarte R.T.D., Nóbrega F., Nakayama C.R., Pellizari V.H. Brazilian research on extremophiles in the context of astrobiology. Int. J. Astrobiol. 2012;11(4):325–333. doi: 10.1017/S1473550412000249. - DOI
    1. Morozkina E.V., Slutskaia E.S., Fedorova T.V., Tugaĭ T.I., Golubeva L.I., Koroleva O.V. Extremophilic microorganisms: biochemical adaptation and biotechnological application. Prikl. Biokhim. Mikrobiol. 2010;46(1):5–20. doi: 10.1134/S0003683810010011. [review]. - DOI - PubMed
    1. Brininger C., Spradlin S., Cobani L., Evilia C. The more adaptive to change, the more likely you are to survive: Protein adaptation in extremophiles. Semin. Cell Dev. Biol. 2018;84:158–169. doi: 10.1016/j.semcdb.2017.12.016. - DOI - PubMed

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