Sustained Remission of Lupus Panniculitis Treated With Hydroxychloroquine in a Patient With Crohn's Disease: A Case Report
- PMID: 33072463
- PMCID: PMC7560489
- DOI: 10.7759/cureus.10455
Sustained Remission of Lupus Panniculitis Treated With Hydroxychloroquine in a Patient With Crohn's Disease: A Case Report
Abstract
Extraintestinal manifestations (EIM) in inflammatory bowel disease (IBD) are common including cutaneous manifestations that either precede or follow manifestations of IBD. Cutaneous manifestations of IBD include erythema nodosum, pyoderma gangrenosum, oral lesions, and Sweet's syndrome. Cutaneous manifestations of IBD tend to recur and extensive cases may require maintenance management with immunomodulators or biologics. However, the complications and adverse effects of long-term therapy with immunosuppressive agents are numerous and need to be considered before their initiation. We report a case of a Crohn's disease patient with recurrent and debilitating cutaneous manifestation of lupus panniculitis that had sustained remission with hydroxychloroquine.
Keywords: crohn's disease; cutaneous manifestations of inflammatory bowel disease; extraintestinal manifestations in inflammatory bowel disease; hydroxychloroquine; inflammatory bowel disease; lupus panniculitis.
Copyright © 2020, Zheng et al.
Conflict of interest statement
The authors have declared that no competing interests exist.
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References
-
- Autoimmune Disorders and Extraintestinal Manifestations in First-degree Familial and Sporadic Inflammatory Bowel Disease. Ricart E, Panaccione R, Loftus EV, et al. Inflammatory Bowel Diseases. 2004;10:207–214. - PubMed
-
- The Extra-Intestinal Complications Of Crohnʼs Disease And Ulcerative Colitis: A Study Of 700 Patients. Greenstein AJ, Janowitz HD, Sachar DB. Medicine. 1976;55:401–412. - PubMed
-
- Lupus panniculitis: clinical perspectives from a case series. Martens PB, Moder KG, Ahmed I. https://pubmed.ncbi.nlm.nih.gov/9918242/ J Rheumatol. 1999;26:68–72. - PubMed
-
- The histopathology of lupus erythematosus panniculitis. Sánchez NP, Peters MS, Winkelmann RK. J Am Acad Dermatol. 1981;5:673–680. - PubMed
-
- Long-term complications, extraintestinal manifestations, and mortality in adult Crohnʼs disease in population-based cohorts. Peyrin-Biroulet L, Loftus EV, Colombel J-F, Sandborn WJ. Inflammatory Bowel Diseases. 2011;17:471–478. - PubMed
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