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Case Reports
. 2020 Dec;2(15):2348-2352.
doi: 10.1016/j.jaccas.2020.09.031. Epub 2020 Oct 12.

Reversible Myocardial Injury Associated With SARS-CoV-2 in an Infant

Madhu Sharma  1 , Samuel Gorstein  2 , Margaret L Aldrich  3 , Daphne T Hsu  1 , Nadine F Choueiter  1
Affiliations
Case Reports

Reversible Myocardial Injury Associated With SARS-CoV-2 in an Infant

Madhu Sharma et al. JACC Case Rep. 2020 Dec.

Abstract

Coronavirus disease-2019 is caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) and has been associated with myocardial dysfunction and heart failure in adult patients. We report a case of reversible myocardial injury and heart failure in an infant with SARS-CoV-2 infection. (Level of Difficulty: Intermediate.).

Keywords: COVID-19, coronavirus disease-2019; CRP, C-reactive protein; DOI, day of illness; ECG, electrocardiogram; LVEF, left ventricular ejection fraction; MR, mitral regurgitation; NT-proBNP, N-terminal pro-B natriuretic peptide; SARS-CoV-2, severe acute respiratory syndrome-coronavirus-2; TnT, Troponin T; coronavirus disease-2019; pediatrics; reversible myocardial injury.

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Conflict of interest statement

The authors have reported that they have no relationships relevant to the contents of this paper to disclose.

Figures

None
Graphical abstract
Figure 1
Figure 1
Chest Radiograph Chest radiograph showing cardiomegaly, bibasilar opacities, and right upper lobe atelectasis.
Figure 2
Figure 2
Electrocardiograms (A) 12-lead electrocardiogram with sinus tachycardia, nonspecific ST-segment depression and T-wave inversions in anterolateral and inferior leads and prominent mid-precordial voltage. (B) Follow-up electrocardiogram showing sinus rhythm, and normalization of T waves in anterolateral and inferior leads.
Figure 3
Figure 3
Clinical Data Trends (A) Selected laboratory trends from admission day of illness 1 through day of illness 14. (B) Trends of left ventricular end diastolic volume (LVEDV) z scores and left ventricular ejection fraction (LVEF) on echocardiogram. CRP = C-reactive protein; NT-proBNP = N-terminal pro-brain natriuretic peptide.
See this image and copyright information in PMC

References

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