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. 2021 Jan:102:226-232.
doi: 10.1016/j.ijid.2020.10.024. Epub 2020 Oct 16.

Presenting Symptoms and Predictors of Poor Outcomes Among 2,184 Patients with COVID-19 in Lagos State, Nigeria

Akin Abayomi  1 , Oluwakemi Odukoya  2 , Akin Osibogun  3 , Ololade Wright  4 , Bisola Adebayo  4 , Mobolanle Balogun  2 , Ismael Abdus-Salam  1 , Abimbola Bowale  5 , Bamidele Mutiu  6 , Babatunde Saka  6 , Moyosore Adejumo  1 , Sam Yenyi  7 , Rotimi Agbolagorite  1 , Oluwatosin Onasanya  8 , Eniola Erinosho  8 , Joshua Obasanya  9 , Olu Adejumo  5 , Sunday Adesola  5 , Yewande Oshodi  10 , Iorhen E Akase  11 , Shina Ogunbiyi  5 , Dayo Lajide  1 , Femi Erinoso  12 , Hussein Abdur-Razzaq  1
Affiliations

Presenting Symptoms and Predictors of Poor Outcomes Among 2,184 Patients with COVID-19 in Lagos State, Nigeria

Akin Abayomi et al. Int J Infect Dis. 2021 Jan.

Abstract

Introduction: Lagos state remains the epicentre of COVID-19 in Nigeria. We describe the symptoms and signs of the first 2,184 PCR-confirmed COVID-19 patients admitted at COVID-19 treatment centers in Lagos State. We also assessed the relationship between patients' presenting symptoms, sociodemographic and clinical characteristics and COVID-19 deaths..

Methods: Medical records of PCR-confirmed COVID-19 patients were extracted and analyzed for their symptoms, symptom severity, presence of comorbidities and outcome.

Results: The ages of the patients ranged from 4 days to 98 years with a mean of 43.0(16.0) years. Of the patients who presented with symptoms, cough (19.3%) was the most common presenting symptom. This was followed by fever (13.7%) and difficulty in breathing, (10.9%). The most significant clinical predictor of death was the severity of symptoms and signs at presentation. Difficulty in breathing was the most significant symptom predictor of COVID-19 death (OR:19.26 95% CI 10.95-33.88). The case fatality rate was 4.3%.

Conclusion: Primary care physicians and COVID-19 frontline workers should maintain a high index of suspicion and prioritize the care of patients presenting with these symptoms. Community members should be educated on such predictors and ensure that patients with these symptoms seek care early to reduce the risk of deaths associated with COVID-19.

Keywords: COVID-19; Death; Nigeria; Symptoms.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

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Fig. 2
Pattern of presentation of patients presenting wth dyspnoea
See this image and copyright information in PMC

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