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. 2020 Oct 15;8(4):37.
doi: 10.3390/diseases8040037.

Hepatitis C Virus Infection Increases Fatigue in Health Care Workers

Vito Emanuele Catania  1 , Giulia Malaguarnera  2 , Giorgia Fiorenza  2 , Eleonora Margherita Chisari  3 , Anna Rita Lipari  4 , Valentino Gallina  4   5 , Manuela Pennisi  6 , Giuseppe Lanza  7 , Michele Malaguarnera  2
Affiliations

Hepatitis C Virus Infection Increases Fatigue in Health Care Workers

Vito Emanuele Catania et al. Diseases. .

Abstract

Fatigue is a common state associated with a weakening or depletion of one's physical and mental resources, that leads to the inability to continue the individual functioning at a normal level of activity. Frequently, fatigue represents a response to infections, inflammation and autoimmune diseases. The scope of this study was to evaluate the fatigue in healthcare workers with and without hepatitis C virus (HCV) infection. Mental, physical and severity fatigue were evaluated through Krupp, Wessely and Powell fatigue scale. Anti-HCV antibodies, HCV RNA and HCV genotypes were also measured. Physical, mental and severity fatigue were higher in healthcare workers with HCV infection than the healthcare workers without infection (p < 0.01). Our data showed a direct link between fatigue and HCV infection in healthcare workers. Further studies are needed to evaluate HCV antiviral treatments on fatigue severity and on quality of life in healthcare workers.

Keywords: HCV; fatigue; healthcare workers.

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Conflict of interest statement

The authors declare no conflict of interest.

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